Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris

G. Moore; S. Schelenz; A. M. Borman; E. M. Johnson; C. S. Brown

doi:10.1016/j.jhin.2017.08.019

Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris

G. Moore^*, S. Schelenz, A. M. Borman, E. M. Johnson, C. S. Brown

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

76 Citations (Scopus)

Abstract

Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol.

Original language	English
Pages (from-to)	371-375
Number of pages	5
Journal	Journal of Hospital Infection
Volume	97
Issue number	4
DOIs	https://doi.org/10.1016/j.jhin.2017.08.019
Publication status	Published - Dec 2017

Bibliographical note

Publisher Copyright:
© 2017

Keywords

Candida auris
Chlorhexidine gluconate
Chlorine
Povidone-iodine
Quantitative suspension test

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jhin.2017.08.019

Cite this

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title = "Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris",

abstract = "Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol.",

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doi = "10.1016/j.jhin.2017.08.019",

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AU - Moore, G.

AU - Schelenz, S.

AU - Borman, A. M.

AU - Johnson, E. M.

AU - Brown, C. S.

PY - 2017/12

Y1 - 2017/12

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AB - Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol.

KW - Candida auris

KW - Chlorhexidine gluconate

KW - Chlorine

KW - Povidone-iodine

KW - Quantitative suspension test

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Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris

Abstract

Bibliographical note

Keywords

UN SDGs

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