TY - JOUR
T1 - Trends in penile cancer
T2 - a comparative study between Australia, England and Wales, and the US
AU - Sewell, James
AU - Ranasinghe, Weranja
AU - De Silva, Daswin
AU - Ayres, Ben
AU - Ranasinghe, Tamra
AU - Hounsome, Luke
AU - Verne, Julia
AU - Persad, Raj
N1 - Publisher Copyright:
© 2015, Sewell et al.
PY - 2015/12/18
Y1 - 2015/12/18
N2 - Purpose: To investigate and compare the trends in incidence and mortality of penile cancer between Australia, England and Wales, and the US, and provide hypotheses for these trends. Methods: Cancer registry data from 1982 to 2005 inclusive were obtained from Australia, England and Wales, and the United States. From these data, age-specific, -standardised and mortality:incidence ratios were calculated, and compared. Results: The overall incidence of penile cancer in England and Wales (1.44 per 100,000 man-years) was higher than in Australia (0.80 per 100,000), and the US (0.66 per 100,000). Incidence of penile cancer in all three countries has remained relatively stable over time. Similarly, although the mortality rates were also higher in England and Wales (0.37 per 100,000 man-years) compared to Australia (0.18 per 100,000) and the US (0.15 per 100,000), the mortality/incidence ratios were similar for all three countries. Conclusions: Penile cancer incidence is low, affecting mainly older men. Rates differ between the three countries, being twice as common in England and Wales as in the other studied regions. Circumcision rates have a potential influence on these rates but are not the sole explanation for the variation.
AB - Purpose: To investigate and compare the trends in incidence and mortality of penile cancer between Australia, England and Wales, and the US, and provide hypotheses for these trends. Methods: Cancer registry data from 1982 to 2005 inclusive were obtained from Australia, England and Wales, and the United States. From these data, age-specific, -standardised and mortality:incidence ratios were calculated, and compared. Results: The overall incidence of penile cancer in England and Wales (1.44 per 100,000 man-years) was higher than in Australia (0.80 per 100,000), and the US (0.66 per 100,000). Incidence of penile cancer in all three countries has remained relatively stable over time. Similarly, although the mortality rates were also higher in England and Wales (0.37 per 100,000 man-years) compared to Australia (0.18 per 100,000) and the US (0.15 per 100,000), the mortality/incidence ratios were similar for all three countries. Conclusions: Penile cancer incidence is low, affecting mainly older men. Rates differ between the three countries, being twice as common in England and Wales as in the other studied regions. Circumcision rates have a potential influence on these rates but are not the sole explanation for the variation.
KW - Carcinoma
KW - Circumcision
KW - Incidence
KW - Male
KW - Penile neoplasms
KW - Squamous cell
UR - http://www.scopus.com/inward/record.url?scp=84939228211&partnerID=8YFLogxK
U2 - 10.1186/s40064-015-1191-4
DO - 10.1186/s40064-015-1191-4
M3 - Article
AN - SCOPUS:84939228211
SN - 2193-1801
VL - 4
JO - SpringerPlus
JF - SpringerPlus
IS - 1
M1 - 420
ER -
