Tracking the uptake of outcomes of hepatitis B virus testing using laboratory data in Victoria, 2011-16: A population-level cohort study

behalf of the ACCESS collaboration

doi:10.1071/SH18102

Tracking the uptake of outcomes of hepatitis B virus testing using laboratory data in Victoria, 2011-16: A population-level cohort study

behalf of the ACCESS collaboration

Research output: Contribution to journal › Article › peer-review

Abstract

Background: A priority area in the 2016 Victorian Hepatitis B Strategy is to increase diagnostic testing. This study describes hepatitis B testing and positivity trends in Victoria between 2011 and 2016 using data from a national laboratory sentinel surveillance system. Methods: Line-listed diagnostic and monitoring hepatitis B testing data among Victorian individuals were collated from six laboratories participating in the Australian Collaboration for Coordinated Enhanced Sentinel Surveillance (ACCESS) of sexually transmissible infections and blood-borne viruses. Diagnostic tests included hepatitis B surface antigen (HBsAg)-only tests and guideline-based hepatitis B tests (defined as a single test event for HBsAg, hepatitis B surface antibody and hepatitis B core antibody). Using available data, the outcomes of testing and/or infection were further classified. Measures reported include the total number of HBsAg and guideline-based tests conducted and the proportion positive, classified as either HBsAg positive or chronic hepatitis B infection. Results: The number of HBsAg tests decreased slightly each year between 2011 and 2016 (from 91 043 in 2011 to 79 664 in 2016; P < 0.001), whereas the number of guideline-based hepatitis B tests increased (from 8732 in 2011 to 16 085 in 2016; P <0.001). The proportion of individuals classified as having chronic infection decreased from 25% in 2011 to 7% in 2016, whereas the proportion classified as susceptible and immune due to vaccination increased (from 29% to 39%, and from 27% to 34%, respectively; P < 0.001). Conclusions: The study findings indicate an increased uptake of guideline-based hepatitis B testing. The ongoing collection of testing data can help monitor progress towards implementation of the Victorian Hepatitis B Strategy.

Original language	English
Pages (from-to)	358-366
Number of pages	9
Journal	Sexual Health
Volume	16
Issue number	4
DOIs	https://doi.org/10.1071/SH18102
Publication status	Published - 2019
Externally published	Yes

Bibliographical note

Funding Information:
The authors gratefully acknowledge funding received for ACCESS from the Australian Department of Health, as well as additional support from the Victorian Department of Health and Human Services and NSW Health. The authors also gratefully acknowledge the contribution of pathology laboratories that have agreed to participate in this study. Caroline van Gemert was supported by an Australian Government Research Training Program Scholarship. Margaret Hellard is supported by an Australian National Health and Medical Research Council Senior Research Fellowship. The Burnet Institute gratefully acknowledges the contribution of the Victorian Operational Infrastructure Support Program to this work. This research did not receive any specific funding.

Publisher Copyright:
© 2019 CSIRO.

Keywords

communicable disease control
surveillance
viral hepatitis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1071/SH18102

Cite this

@article{339b3ae75718409cb17e2f28cc5ccf8a,

title = "Tracking the uptake of outcomes of hepatitis B virus testing using laboratory data in Victoria, 2011-16: A population-level cohort study",

abstract = "Background: A priority area in the 2016 Victorian Hepatitis B Strategy is to increase diagnostic testing. This study describes hepatitis B testing and positivity trends in Victoria between 2011 and 2016 using data from a national laboratory sentinel surveillance system. Methods: Line-listed diagnostic and monitoring hepatitis B testing data among Victorian individuals were collated from six laboratories participating in the Australian Collaboration for Coordinated Enhanced Sentinel Surveillance (ACCESS) of sexually transmissible infections and blood-borne viruses. Diagnostic tests included hepatitis B surface antigen (HBsAg)-only tests and guideline-based hepatitis B tests (defined as a single test event for HBsAg, hepatitis B surface antibody and hepatitis B core antibody). Using available data, the outcomes of testing and/or infection were further classified. Measures reported include the total number of HBsAg and guideline-based tests conducted and the proportion positive, classified as either HBsAg positive or chronic hepatitis B infection. Results: The number of HBsAg tests decreased slightly each year between 2011 and 2016 (from 91 043 in 2011 to 79 664 in 2016; P < 0.001), whereas the number of guideline-based hepatitis B tests increased (from 8732 in 2011 to 16 085 in 2016; P <0.001). The proportion of individuals classified as having chronic infection decreased from 25% in 2011 to 7% in 2016, whereas the proportion classified as susceptible and immune due to vaccination increased (from 29% to 39%, and from 27% to 34%, respectively; P < 0.001). Conclusions: The study findings indicate an increased uptake of guideline-based hepatitis B testing. The ongoing collection of testing data can help monitor progress towards implementation of the Victorian Hepatitis B Strategy.",

keywords = "communicable disease control, surveillance, viral hepatitis",

author = "{behalf of the ACCESS collaboration} and {Van Gemert}, Caroline and Wayne Dimech and Mark Stoove and Rebecca Guy and Jess Howell and Scott Bowden and Suellen Nicholson and Stella Pendle and Basil Donovan and Margaret Hellard and {Van Gemert}, Caroline and Carol El-Hayek and Denton Callandar and Jason Asselin and Clarissa Moreira and Smith, {Lucy Watchirs} and Long Nguyen and Gijo Thomas",

note = "Funding Information: The authors gratefully acknowledge funding received for ACCESS from the Australian Department of Health, as well as additional support from the Victorian Department of Health and Human Services and NSW Health. The authors also gratefully acknowledge the contribution of pathology laboratories that have agreed to participate in this study. Caroline van Gemert was supported by an Australian Government Research Training Program Scholarship. Margaret Hellard is supported by an Australian National Health and Medical Research Council Senior Research Fellowship. The Burnet Institute gratefully acknowledges the contribution of the Victorian Operational Infrastructure Support Program to this work. This research did not receive any specific funding. Publisher Copyright: {\textcopyright} 2019 CSIRO.",

year = "2019",

doi = "10.1071/SH18102",

language = "English",

volume = "16",

pages = "358--366",

journal = "Sexual Health",

issn = "1448-5028",

publisher = "CSIRO Publishing",

number = "4",

}

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T1 - Tracking the uptake of outcomes of hepatitis B virus testing using laboratory data in Victoria, 2011-16

T2 - A population-level cohort study

AU - behalf of the ACCESS collaboration

AU - Van Gemert, Caroline

AU - Dimech, Wayne

AU - Stoove, Mark

AU - Guy, Rebecca

AU - Howell, Jess

AU - Bowden, Scott

AU - Nicholson, Suellen

AU - Pendle, Stella

AU - Donovan, Basil

AU - Hellard, Margaret

AU - Van Gemert, Caroline

AU - El-Hayek, Carol

AU - Callandar, Denton

AU - Asselin, Jason

AU - Moreira, Clarissa

AU - Smith, Lucy Watchirs

AU - Nguyen, Long

AU - Thomas, Gijo

N1 - Funding Information: The authors gratefully acknowledge funding received for ACCESS from the Australian Department of Health, as well as additional support from the Victorian Department of Health and Human Services and NSW Health. The authors also gratefully acknowledge the contribution of pathology laboratories that have agreed to participate in this study. Caroline van Gemert was supported by an Australian Government Research Training Program Scholarship. Margaret Hellard is supported by an Australian National Health and Medical Research Council Senior Research Fellowship. The Burnet Institute gratefully acknowledges the contribution of the Victorian Operational Infrastructure Support Program to this work. This research did not receive any specific funding. Publisher Copyright: © 2019 CSIRO.

PY - 2019

Y1 - 2019

N2 - Background: A priority area in the 2016 Victorian Hepatitis B Strategy is to increase diagnostic testing. This study describes hepatitis B testing and positivity trends in Victoria between 2011 and 2016 using data from a national laboratory sentinel surveillance system. Methods: Line-listed diagnostic and monitoring hepatitis B testing data among Victorian individuals were collated from six laboratories participating in the Australian Collaboration for Coordinated Enhanced Sentinel Surveillance (ACCESS) of sexually transmissible infections and blood-borne viruses. Diagnostic tests included hepatitis B surface antigen (HBsAg)-only tests and guideline-based hepatitis B tests (defined as a single test event for HBsAg, hepatitis B surface antibody and hepatitis B core antibody). Using available data, the outcomes of testing and/or infection were further classified. Measures reported include the total number of HBsAg and guideline-based tests conducted and the proportion positive, classified as either HBsAg positive or chronic hepatitis B infection. Results: The number of HBsAg tests decreased slightly each year between 2011 and 2016 (from 91 043 in 2011 to 79 664 in 2016; P < 0.001), whereas the number of guideline-based hepatitis B tests increased (from 8732 in 2011 to 16 085 in 2016; P <0.001). The proportion of individuals classified as having chronic infection decreased from 25% in 2011 to 7% in 2016, whereas the proportion classified as susceptible and immune due to vaccination increased (from 29% to 39%, and from 27% to 34%, respectively; P < 0.001). Conclusions: The study findings indicate an increased uptake of guideline-based hepatitis B testing. The ongoing collection of testing data can help monitor progress towards implementation of the Victorian Hepatitis B Strategy.

AB - Background: A priority area in the 2016 Victorian Hepatitis B Strategy is to increase diagnostic testing. This study describes hepatitis B testing and positivity trends in Victoria between 2011 and 2016 using data from a national laboratory sentinel surveillance system. Methods: Line-listed diagnostic and monitoring hepatitis B testing data among Victorian individuals were collated from six laboratories participating in the Australian Collaboration for Coordinated Enhanced Sentinel Surveillance (ACCESS) of sexually transmissible infections and blood-borne viruses. Diagnostic tests included hepatitis B surface antigen (HBsAg)-only tests and guideline-based hepatitis B tests (defined as a single test event for HBsAg, hepatitis B surface antibody and hepatitis B core antibody). Using available data, the outcomes of testing and/or infection were further classified. Measures reported include the total number of HBsAg and guideline-based tests conducted and the proportion positive, classified as either HBsAg positive or chronic hepatitis B infection. Results: The number of HBsAg tests decreased slightly each year between 2011 and 2016 (from 91 043 in 2011 to 79 664 in 2016; P < 0.001), whereas the number of guideline-based hepatitis B tests increased (from 8732 in 2011 to 16 085 in 2016; P <0.001). The proportion of individuals classified as having chronic infection decreased from 25% in 2011 to 7% in 2016, whereas the proportion classified as susceptible and immune due to vaccination increased (from 29% to 39%, and from 27% to 34%, respectively; P < 0.001). Conclusions: The study findings indicate an increased uptake of guideline-based hepatitis B testing. The ongoing collection of testing data can help monitor progress towards implementation of the Victorian Hepatitis B Strategy.

KW - communicable disease control

KW - surveillance

KW - viral hepatitis

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SN - 1448-5028

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SP - 358

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JO - Sexual Health

JF - Sexual Health

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ER -

Tracking the uptake of outcomes of hepatitis B virus testing using laboratory data in Victoria, 2011-16: A population-level cohort study

Abstract

Bibliographical note

Keywords

UN SDGs

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