Towards a genomics-informed, real-time, global pathogen surveillance system

Jennifer L. Gardy*, Nicholas J. Loman

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

205 Citations (Scopus)

Abstract

The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable sequencing of pathogen genomes — now a staple of the public health microbiology laboratory in well-resourced settings — can affect each of these areas. Coupling genomic diagnostics and epidemiology to innovative digital disease detection platforms raises the possibility of an open, global, digital pathogen surveillance system. When informed by a One Health approach, in which human, animal and environmental health are considered together, such a genomics-based system has profound potential to improve public health in settings lacking robust laboratory capacity.

Original languageEnglish
Pages (from-to)9-20
Number of pages12
JournalNature Reviews Genetics
Volume19
Issue number1
DOIs
Publication statusPublished - 2018
Externally publishedYes

Bibliographical note

Funding Information:
J.L.G. is funded by the Canada Research Chairs and Michael Smith Foundation for Health Research programmes.

Publisher Copyright:
© 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.

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