The success of HIV combination prevention: The Dean Street model

Nicolò Girometti*, Valerie Delpech, Sheena McCormack, Jameel Khawam, Sophie Nash, Dana Ogaz, Hamish Mohammed, Keerti Gedela, Diarmuid Nugent, Sheel Patel, Tara Suchak, Victoria Tittle, Alan McOwan, Gary Whitlock

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


The 56 Dean Street combination prevention model, a strong engagement with the LGBTQI community and flexible services adapted to users’ changing needs led to an 80% drop in HIV diagnoses in gay, bisexual and other men who have sex with men (GBMSM) from 2015 to 2017. We describe the service changes at 56 Dean Street since 2012 which resulted in an increase in the frequency of HIV testing, the introduction of pre-exposure prophylaxis, earlier HIV diagnosis and a shorter time to viral suppression in those living with HIV. This model could be adapted to deliver similar results in those settings of high HIV prevalence among GBMSM and where access to technological innovation in healthcare and engagement with the community can be achieved.

Original languageEnglish
Pages (from-to)892-897
Number of pages6
JournalHIV Medicine
Issue number10
Early online date29 Jul 2021
Publication statusPublished - Nov 2021

Bibliographical note

Funding Information: The authors declare there are no conflicts of interest.

Open Access: No Open Access licence.

Publisher Copyright: © 2021 British HIV Association

Citation: Girometti, N, Delpech, V, McCormack, S, et al. The success of HIV combination prevention: The Dean Street model. HIV Med. 2021; 22: 892– 897.



  • HIV
  • HIV combination prevention
  • HIV prevention
  • pre-exposure prophylaxis (PrEP)
  • treatment-as-prevention (TasP)
  • MEN
  • SEX


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