The role of aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use: results of a pooled-analysis from seven European countries

Clémence Baudin, Marie Lefèvre, Wolfgang Babisch, Ennio Cadum, Patricia Champelovier, Konstantina Dimakopoulou, Danny Houthuijs, Jacques Lambert, Bernard Laumon, Göran Pershagen, Stephen Stansfeld, Venetia Velonaki, Anna L. Hansell, Anne Sophie Evrard*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Background: Few studies have considered aircraft noise annoyance and noise sensitivity in analyses of the health effects of aircraft noise, especially in relation to medication use. This study aims to investigate the moderating and mediating role of these two factors in the relationship between aircraft noise levels and medication use among 5860 residents of ten European airports included in the HYENA and DEBATS studies. Methods: Information on aircraft noise annoyance, noise sensitivity, medication use, and demographic, socio-economic and lifestyle factors was collected during a face-to-face interview at home. Medication was coded according to the Anatomical Therapeutic Chemical (ATC) classification. Outdoor aircraft noise exposure was estimated by linking the participant’s home address to noise contours using Geographical Information Systems (GIS) methods. Logistic regressions with adjustment for potential confounding factors were used. In addition, Baron and Kenny’s recommendations were followed to investigate the moderating and mediating effects of aircraft noise annoyance and noise sensitivity. Results: A significant association was found between aircraft noise levels at night and antihypertensive medication only in the UK (OR = 1.43, 95%CI 1.19–1.73 for a 10 dB(A)-increase in Lnight). No association was found with other medications. Aircraft noise annoyance was significantly associated with the use of antihypertensive medication (OR = 1.33, 95%CI 1.14–1.56), anxiolytics (OR = 1.48, 95%CI 1.08–2.05), hypnotics and sedatives (OR = 1.60, 95%CI 1.07–2.39), and antasthmatics (OR = 1.44, 95%CI 1.07–1.96), with no difference between countries. Noise sensitivity was significantly associated with almost all medications, with the exception of the use of antasthmatics, showing an increase in ORs with the level of noise sensitivity, with differences in ORs among countries only for the use of antihypertensive medication. The results also suggested a mediating role of aircraft noise annoyance and a modifying role of both aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use. Conclusions: The present study is consistent with the results of the small number of studies available to date suggesting that both aircraft noise annoyance and noise sensitivity should be taken into account in analyses of the health effects of exposure to aircraft noise.

Original languageEnglish
Article number300
JournalBMC Public Health
Volume21
Issue number1
DOIs
Publication statusPublished - Dec 2021
Externally publishedYes

Bibliographical note

Funding Information:
The DEBATS study was supported by funds from the French Ministry of Health, the French Ministry of the Environment, and the French Civil Aviation Authority.

Funding Information:
The present study was sustained by a grant from the European and International Affairs Department (DAEI) of IFSTTAR (French Institute of science and technology for transport, development and networks).

Funding Information:
The HYENA study was funded by a grant from the European Commission (Directorate General Research) in the Fifth Framework Programme, Quality of Life and Management of Living Resources, Key Action 4 - Environment and Health (grant QLRT-2001-02501).

Funding Information:
For HYENA study: Thanks to Lars Jarup, HYENA principal investigator and other members of the HYENA study team responsible for conducting the study. Thanks to the aviation administration and the road administration in each of the participating countries for their contribution to the noise exposure assessment. For DEBATS study: Thanks to the Airport Pollution Control Authority (Acnusa) for requesting the French Institute of Science and Technology for Transport, Development and Networks (Ifsttar) to carry out this study; thanks to Paris Airports and the French Civil Aviation Authority for providing noise exposure maps. The authors thank Sarah Floud for data extraction and preparation and variable interpretation. The authors are grateful to all the participants in both HYENA and DEBATS studies and their interviewers. They are also grateful to Lise Giorgis Allemand for her skilful revision of the manuscript.

Publisher Copyright:
© 2021, The Author(s).

Keywords

  • Aircraft noise annoyance
  • Aircraft noise exposure
  • Medication use
  • Noise sensitivity

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