The induction of chromosome aberrations in human lymphocytes by accelerated charged particles

Alan Edwards; D. C. Lloyd; J. S. Prosser

doi:10.1093/rpd/13.1-4.205

The induction of chromosome aberrations in human lymphocytes by accelerated charged particles

Alan Edwards, D. C. Lloyd, J. S. Prosser

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

The induction of chromosome aberrations in human lymphocytes by different radiations has been studied for many years. Results have been published for several qualities of radiation which include X rays, γ rays, neutrons of various energies and alpha particles. For each of these the linear quadratic equation has fitted the data although for some the dose-squared coefficient is zero. This work has progressed to the use of accelerated charged particles for track segment irradiation of blood, that is, exposure within a narrow range of LET. This paper presents results produced by 8.7 MeV protons and 23 MeV helium-3 ions. A preliminary analysis based on the microdosimetric properties of the radiations compares these results with predictions made from the earlier neutron and alpha particle measurements.

Original language	English
Pages (from-to)	205-209
Number of pages	5
Journal	Radiation Protection Dosimetry
Volume	13
Issue number	1-4
DOIs	https://doi.org/10.1093/rpd/13.1-4.205
Publication status	Published - 1985

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AB - The induction of chromosome aberrations in human lymphocytes by different radiations has been studied for many years. Results have been published for several qualities of radiation which include X rays, γ rays, neutrons of various energies and alpha particles. For each of these the linear quadratic equation has fitted the data although for some the dose-squared coefficient is zero. This work has progressed to the use of accelerated charged particles for track segment irradiation of blood, that is, exposure within a narrow range of LET. This paper presents results produced by 8.7 MeV protons and 23 MeV helium-3 ions. A preliminary analysis based on the microdosimetric properties of the radiations compares these results with predictions made from the earlier neutron and alpha particle measurements.

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The induction of chromosome aberrations in human lymphocytes by accelerated charged particles

Abstract

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