The gastrointestinal absorption of 63Ni and 95Nb in adult and neonatal rats: Effect of the chemical form administered

F. Paquet*, P. Houpert, M. Verry, G. Grillon, John Harrison, H. Métivier

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)

    Abstract

    The gastrointestinal absorption of 63Ni and 95Nb has been determined in adult and neonatal rats after administration as various chemical forms. For 63Ni, f1 was determined as (4.3 ± 1.4) X 10-2, (5.1 ± 2.1) X 10-2 and (3.3 ± 1.5) X 10-2, for the citrate, oxalate and chloride forms, respectively. For 95Nb, the corresponding f1 values were (1.25 ± 0.37) X 10-2, (0.37 ± 0.15) X 10-2 and (0.24 ± 0.07) X 10-2, respectively. When radionuclides were administered to 1 day old animals, the retention increased by factors of up to 40 and 200 for 63Ni-chloride and 95Nb-oxalate respectively. All these results are discussed with respect to the ICRP recommendations.

    Original languageEnglish
    Pages (from-to)191-195
    Number of pages5
    JournalRadiation Protection Dosimetry
    Volume79
    Issue number1-4
    DOIs
    Publication statusPublished - 1998

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