The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region

A. Nardone; F. de Ory; M. Carton; D. Cohen; P. van Damme; I. Davidkin; M. C. Rota; H. de Melker; J. Mossong; M. Slacikova; A. Tischer; N. Andrews; G. Berbers; G. Gabutti; N. Gay; L. Jones; S. Jokinen; G. Kafatos; M. V.Martínez de Aragón; F. Schneider; Z. Smetana; B. Vargova; R. Vranckx; E. Miller

doi:10.1016/j.vaccine.2007.07.036

The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region

A. Nardone^*, F. de Ory, M. Carton, D. Cohen, P. van Damme, I. Davidkin, M. C. Rota, H. de Melker, J. Mossong, M. Slacikova, A. Tischer, N. Andrews, G. Berbers, G. Gabutti, N. Gay, L. Jones, S. Jokinen, G. Kafatos, M. V.Martínez de Aragón, F. SchneiderZ. Smetana, B. Vargova, R. Vranckx, E. Miller

^*Corresponding author for this work

Immunisation Hepatitis and Blood Safety

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Abstract

The European sero-epidemiology network (ESEN2) aims to standardise serological surveillance of varicella zoster virus (VZV) in 11 participant countries. In each country, serum banks were collected between 1996 and 2003 and tested for VZV antibodies. Assay results were standardised so that international comparisons could be made. Age-specific forces of infection were calculated for three age groups (<5, 5-9 and ≥10 years of age) and used to estimate the base reproduction number (R₀) and the herd immunity threshold (H). Most VZV infection occurred in childhood, but there was a wide variation in transmissibility, with R₀ ranging from 16.9 in the Netherlands to 3.3 in Italy. Herd immunity thresholds varied from 70% in Italy to 94% in the Netherlands. There are substantial differences in VZV sero-epidemiology within the European region, which will need to be taken into account in designing national policies regarding VZV vaccination.

Original language	English
Pages (from-to)	7866-7872
Number of pages	7
Journal	Vaccine
Volume	25
Issue number	45
DOIs	https://doi.org/10.1016/j.vaccine.2007.07.036
Publication status	Published - 7 Nov 2007

Bibliographical note

Funding Information:
This work was undertaken with funding from the European Commission (contract number QLK2-CT-2000-00542), from national governments and other national funding sources.

Keywords

Seroepidemiology
Vaccination
Varicella zoster virus

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.vaccine.2007.07.036

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Nardone, A., de Ory, F., Carton, M., Cohen, D., van Damme, P., Davidkin, I., Rota, M. C., de Melker, H., Mossong, J., Slacikova, M., Tischer, A., Andrews, N., Berbers, G., Gabutti, G., Gay, N., Jones, L., Jokinen, S., Kafatos, G., de Aragón, M. V. M., ... Miller, E. (2007). The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region. Vaccine, 25(45), 7866-7872. https://doi.org/10.1016/j.vaccine.2007.07.036

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title = "The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region",

abstract = "The European sero-epidemiology network (ESEN2) aims to standardise serological surveillance of varicella zoster virus (VZV) in 11 participant countries. In each country, serum banks were collected between 1996 and 2003 and tested for VZV antibodies. Assay results were standardised so that international comparisons could be made. Age-specific forces of infection were calculated for three age groups (<5, 5-9 and ≥10 years of age) and used to estimate the base reproduction number (R0) and the herd immunity threshold (H). Most VZV infection occurred in childhood, but there was a wide variation in transmissibility, with R0 ranging from 16.9 in the Netherlands to 3.3 in Italy. Herd immunity thresholds varied from 70% in Italy to 94% in the Netherlands. There are substantial differences in VZV sero-epidemiology within the European region, which will need to be taken into account in designing national policies regarding VZV vaccination.",

keywords = "Seroepidemiology, Vaccination, Varicella zoster virus",

author = "A. Nardone and {de Ory}, F. and M. Carton and D. Cohen and {van Damme}, P. and I. Davidkin and Rota, {M. C.} and {de Melker}, H. and J. Mossong and M. Slacikova and A. Tischer and N. Andrews and G. Berbers and G. Gabutti and N. Gay and L. Jones and S. Jokinen and G. Kafatos and {de Arag{\'o}n}, {M. V.Mart{\'i}nez} and F. Schneider and Z. Smetana and B. Vargova and R. Vranckx and E. Miller",

note = "Funding Information: This work was undertaken with funding from the European Commission (contract number QLK2-CT-2000-00542), from national governments and other national funding sources. ",

year = "2007",

month = nov,

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doi = "10.1016/j.vaccine.2007.07.036",

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Nardone, A, de Ory, F, Carton, M, Cohen, D, van Damme, P, Davidkin, I, Rota, MC, de Melker, H, Mossong, J, Slacikova, M, Tischer, A, Andrews, N, Berbers, G, Gabutti, G, Gay, N, Jones, L, Jokinen, S, Kafatos, G, de Aragón, MVM, Schneider, F, Smetana, Z, Vargova, B, Vranckx, R & Miller, E 2007, 'The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region', Vaccine, vol. 25, no. 45, pp. 7866-7872. https://doi.org/10.1016/j.vaccine.2007.07.036

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T1 - The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region

AU - Nardone, A.

AU - de Ory, F.

AU - Carton, M.

AU - Cohen, D.

AU - van Damme, P.

AU - Davidkin, I.

AU - Rota, M. C.

AU - de Melker, H.

AU - Mossong, J.

AU - Slacikova, M.

AU - Tischer, A.

AU - Andrews, N.

AU - Berbers, G.

AU - Gabutti, G.

AU - Gay, N.

AU - Jones, L.

AU - Jokinen, S.

AU - Kafatos, G.

AU - de Aragón, M. V.Martínez

AU - Schneider, F.

AU - Smetana, Z.

AU - Vargova, B.

AU - Vranckx, R.

AU - Miller, E.

N1 - Funding Information: This work was undertaken with funding from the European Commission (contract number QLK2-CT-2000-00542), from national governments and other national funding sources.

PY - 2007/11/7

Y1 - 2007/11/7

N2 - The European sero-epidemiology network (ESEN2) aims to standardise serological surveillance of varicella zoster virus (VZV) in 11 participant countries. In each country, serum banks were collected between 1996 and 2003 and tested for VZV antibodies. Assay results were standardised so that international comparisons could be made. Age-specific forces of infection were calculated for three age groups (<5, 5-9 and ≥10 years of age) and used to estimate the base reproduction number (R0) and the herd immunity threshold (H). Most VZV infection occurred in childhood, but there was a wide variation in transmissibility, with R0 ranging from 16.9 in the Netherlands to 3.3 in Italy. Herd immunity thresholds varied from 70% in Italy to 94% in the Netherlands. There are substantial differences in VZV sero-epidemiology within the European region, which will need to be taken into account in designing national policies regarding VZV vaccination.

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KW - Seroepidemiology

KW - Vaccination

KW - Varicella zoster virus

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DO - 10.1016/j.vaccine.2007.07.036

M3 - Article

C2 - 17919788

AN - SCOPUS:35348845129

SN - 0264-410X

VL - 25

SP - 7866

EP - 7872

JO - Vaccine

JF - Vaccine

IS - 45

ER -

The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

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