The challenge of antimicrobial resistance: What economics can contribute

Laurence S.J. Roope; Richard D. Smith; Koen B. Pouwels; James Buchanan; Lucy Abel; Peter Eibich; Christopher C. Butler; Pui San Tan; A. Sarah Walker; Julie V. Robotham; Sarah Wordsworth

doi:10.1126/science.aau4679

The challenge of antimicrobial resistance: What economics can contribute

Laurence S.J. Roope, Richard D. Smith^*, Koen B. Pouwels, James Buchanan, Lucy Abel, Peter Eibich, Christopher C. Butler, Pui San Tan, A. Sarah Walker, Julie V. Robotham, Sarah Wordsworth

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

315 Citations (Scopus)

Abstract

As antibiotic consumption grows, bacteria are becoming increasingly resistant to treatment. Antibiotic resistance undermines much of modern health care, which relies on access to effective antibiotics to prevent and treat infections associated with routine medical procedures. The resulting challenges have much in common with those posed by climate change, which economists have responded to with research that has informed and shaped public policy. Drawing on economic concepts such as externalities and the principal–agent relationship, we suggest how economics can help to solve the challenges arising from increasing resistance to antibiotics. We discuss solutions to the key economic issues, from incentivizing the development of effective new antibiotics to improving antibiotic stewardship through financial mechanisms and regulation.

Original language	English
Article number	eaau4679
Journal	Science
Volume	364
Issue number	6435
DOIs	https://doi.org/10.1126/science.aau4679
Publication status	Published - 5 Apr 2019

Bibliographical note

Publisher Copyright:
© 2017 The Authors.

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title = "The challenge of antimicrobial resistance: What economics can contribute",

abstract = "As antibiotic consumption grows, bacteria are becoming increasingly resistant to treatment. Antibiotic resistance undermines much of modern health care, which relies on access to effective antibiotics to prevent and treat infections associated with routine medical procedures. The resulting challenges have much in common with those posed by climate change, which economists have responded to with research that has informed and shaped public policy. Drawing on economic concepts such as externalities and the principal–agent relationship, we suggest how economics can help to solve the challenges arising from increasing resistance to antibiotics. We discuss solutions to the key economic issues, from incentivizing the development of effective new antibiotics to improving antibiotic stewardship through financial mechanisms and regulation.",

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AU - Roope, Laurence S.J.

AU - Smith, Richard D.

AU - Pouwels, Koen B.

AU - Buchanan, James

AU - Abel, Lucy

AU - Eibich, Peter

AU - Butler, Christopher C.

AU - Tan, Pui San

AU - Sarah Walker, A.

AU - Robotham, Julie V.

AU - Wordsworth, Sarah

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N2 - As antibiotic consumption grows, bacteria are becoming increasingly resistant to treatment. Antibiotic resistance undermines much of modern health care, which relies on access to effective antibiotics to prevent and treat infections associated with routine medical procedures. The resulting challenges have much in common with those posed by climate change, which economists have responded to with research that has informed and shaped public policy. Drawing on economic concepts such as externalities and the principal–agent relationship, we suggest how economics can help to solve the challenges arising from increasing resistance to antibiotics. We discuss solutions to the key economic issues, from incentivizing the development of effective new antibiotics to improving antibiotic stewardship through financial mechanisms and regulation.

AB - As antibiotic consumption grows, bacteria are becoming increasingly resistant to treatment. Antibiotic resistance undermines much of modern health care, which relies on access to effective antibiotics to prevent and treat infections associated with routine medical procedures. The resulting challenges have much in common with those posed by climate change, which economists have responded to with research that has informed and shaped public policy. Drawing on economic concepts such as externalities and the principal–agent relationship, we suggest how economics can help to solve the challenges arising from increasing resistance to antibiotics. We discuss solutions to the key economic issues, from incentivizing the development of effective new antibiotics to improving antibiotic stewardship through financial mechanisms and regulation.

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SN - 0036-8075

VL - 364

JO - Science

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The challenge of antimicrobial resistance: What economics can contribute

Abstract

Bibliographical note

UN SDGs

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