Targeted screening in the UK: A narrow concept with broad application

Anna Bobrowska, Molly Murton, Farah Seedat, Cristina Visintin, Anne Mackie, Robert Steele, John Marshall*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

A recent report on screening in the UK proposed that the responsibility for recommendations on population and targeted screening programmes should be held by one new integrated advisory body. There is no wide international consensus on the definition of targeted screening. Our review identified and compared the defining components of screening terms: targeted, population, selective, and cascade screening, and case finding. Definitions of targeted screening and population screening were clearly demarcated by the eligible population; targeted and selective screening were found to be conceptually interchangeable; cascade screening, whilst conceptually similar to targeted screening across several components, was only used within the context of genetic diseases. There was little consensus between different definitions of case finding. These comparisons contributed to an updated definition of targeted screening. Considerable overlap between definition components across terms implies that a broad range of disease areas may fall into the remit of the new advisory body.

Original languageEnglish
Article number100353
JournalThe Lancet Regional Health - Europe
Volume16
DOIs
Publication statusPublished - May 2022
Externally publishedYes

Bibliographical note

Funding Information:
This study was sponsored by the UK National Screening Committee (UK NSC). The corresponding author confirms that authors were not precluded from accessing data in the study and accepts responsibility to submit for publication.

Funding Information:
Not required. This study was sponsored by the UK National Screening Committee (UK NSC). The corresponding author confirms that authors were not precluded from accessing data in the study and accepts responsibility to submit for publication. The authors acknowledge Eliza McHugh, MChem, and Debbie Nixon, DPhil, from Costello Medical, UK, for medical writing and editorial assistance based on the authors? input and direction. Support for third-party writing assistance for this article, provided by Costello Medical, UK, was funded by the UK NSC in accordance with Good Publication Practice (GPP3) guidelines ( http://www.ismpp.org/gpp3). Requests for access to data should be addressed to the corresponding author.

Publisher Copyright:
© 2022 The Author(s)

Keywords

  • Cascade screening
  • Case finding
  • Population screening
  • Screening
  • Selective screening
  • Targeted screening

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