TY - JOUR
T1 - Systematic review and meta-analyses of incidence for group B streptococcus disease in infants and antimicrobial resistance, China
AU - Ding, Yijun
AU - Wang, Yajuan
AU - Hsia, Yingfen
AU - Russell, Neal
AU - Heath, Paul T.
N1 - Publisher Copyright:
© 2020 Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2020/11
Y1 - 2020/11
N2 - We performed a systematic review and meta-analysis of the incidence, case-fatality rate (CFR), isolate antimicrobial resistance patterns, and serotype and sequence type distributions for invasive group B Streptococcus (GBS) disease in infants <1–89 days of age in China. We searched the PubMed/Medline, Embase, Wanfang, and China National Knowledge Infrastructure databases for research published during January 1, 2000–March 16, 2018, and identified 64 studies. Quality of included studies was assessed by using Cochrane tools. Incidence and CFR were estimated by using random-effects meta-analyses. Overall incidence was 0.55 (95% CI 0.35–0.74) cases/1,000 live births, and the CFR was 5% (95% CI 3%–6%). Incidence of GBS in young infants in China was higher than the estimated global incidence (0.49 cases/1,000 live births) and higher than previous estimates for Asia (0.3 cases/1,000 live births). Our findings suggest that implementation of additional GBS prevention efforts in China, including maternal vaccination, could be beneficial.
AB - We performed a systematic review and meta-analysis of the incidence, case-fatality rate (CFR), isolate antimicrobial resistance patterns, and serotype and sequence type distributions for invasive group B Streptococcus (GBS) disease in infants <1–89 days of age in China. We searched the PubMed/Medline, Embase, Wanfang, and China National Knowledge Infrastructure databases for research published during January 1, 2000–March 16, 2018, and identified 64 studies. Quality of included studies was assessed by using Cochrane tools. Incidence and CFR were estimated by using random-effects meta-analyses. Overall incidence was 0.55 (95% CI 0.35–0.74) cases/1,000 live births, and the CFR was 5% (95% CI 3%–6%). Incidence of GBS in young infants in China was higher than the estimated global incidence (0.49 cases/1,000 live births) and higher than previous estimates for Asia (0.3 cases/1,000 live births). Our findings suggest that implementation of additional GBS prevention efforts in China, including maternal vaccination, could be beneficial.
UR - http://www.scopus.com/inward/record.url?scp=85094221070&partnerID=8YFLogxK
U2 - 10.3201/eid2611.181414
DO - 10.3201/eid2611.181414
M3 - Article
C2 - 33079042
AN - SCOPUS:85094221070
SN - 1080-6040
VL - 26
SP - 2651
EP - 2659
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 11
ER -
