TY - JOUR
T1 - Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand
AU - Wuthiekanun, Vanaporn
AU - Amornchai, Premjit
AU - Saiprom, Natnaree
AU - Chantratita, Narisara
AU - Chierakul, Wirongrong
AU - Koh, Gavin C.K.W.
AU - Chaowagul, Wipada
AU - Day, Nicholas P.J.
AU - Limmathurotsakul, Direk
AU - Peacock, Sharon J.
PY - 2011/11
Y1 - 2011/11
N2 - A 21-year survey conducted in northeast Thailand of antimicrobial resistance to parenteral antimicrobial drugs used to treat melioidosis identified 24/4,021 (0.6%) patients with one or more isolates resistant to ceftazidime (n ∇ 8), amoxicillin-clavulanic acid (n ∇ 4), or both drugs (n ∇ 12). Two cases were identified at admission, and the remainder were detected a median of 15 days after starting antimicrobial therapy. Resistance to carbapenem drugs was not detected. These findings support the current prescribing recommendations for melioidosis.
AB - A 21-year survey conducted in northeast Thailand of antimicrobial resistance to parenteral antimicrobial drugs used to treat melioidosis identified 24/4,021 (0.6%) patients with one or more isolates resistant to ceftazidime (n ∇ 8), amoxicillin-clavulanic acid (n ∇ 4), or both drugs (n ∇ 12). Two cases were identified at admission, and the remainder were detected a median of 15 days after starting antimicrobial therapy. Resistance to carbapenem drugs was not detected. These findings support the current prescribing recommendations for melioidosis.
UR - http://www.scopus.com/inward/record.url?scp=80054710806&partnerID=8YFLogxK
U2 - 10.1128/AAC.05517-11
DO - 10.1128/AAC.05517-11
M3 - Article
C2 - 21876049
AN - SCOPUS:80054710806
SN - 0066-4804
VL - 55
SP - 5388
EP - 5391
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 11
ER -
