TY - JOUR
T1 - Strategies to control pertussis in infants
AU - Amirthalingam, Gayatri
PY - 2013/7
Y1 - 2013/7
N2 - The UK is currently in the midst of a large outbreak of pertussis, with the highest morbidity and mortality occurring in young unimmunised infants. This review considers the potential strategies to optimise control of pertussis in infants, including vaccination of (1) adolescents, (2) close household contacts of newborn infants (cocooning), (3) newborn infants and (4) pregnant women. The paper discusses the evidence base for each of these strategies and considers the rationale for the recent introduction of a temporary vaccination programme for pregnant women in the UK in response to the ongoing outbreak.
AB - The UK is currently in the midst of a large outbreak of pertussis, with the highest morbidity and mortality occurring in young unimmunised infants. This review considers the potential strategies to optimise control of pertussis in infants, including vaccination of (1) adolescents, (2) close household contacts of newborn infants (cocooning), (3) newborn infants and (4) pregnant women. The paper discusses the evidence base for each of these strategies and considers the rationale for the recent introduction of a temporary vaccination programme for pregnant women in the UK in response to the ongoing outbreak.
UR - http://www.scopus.com/inward/record.url?scp=84879636179&partnerID=8YFLogxK
U2 - 10.1136/archdischild-2012-302968
DO - 10.1136/archdischild-2012-302968
M3 - Review article
C2 - 23698594
AN - SCOPUS:84879636179
SN - 0003-9888
VL - 98
SP - 552
EP - 555
JO - Archives of Disease in Childhood
JF - Archives of Disease in Childhood
IS - 7
ER -