Still no evidence of new variant Chlamydia trachomatis in England and Wales

Sarah Alexander*, Filomeno Coelho Da Silva, Fathiya Alhadi, Catherine Ison

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Background: New variant Chlamydia trachomatis (nvCT) remains an important public health concern and in 2008 four cases of nvCT were reported in Scotland. The present study set out to determine whether nvCT was present in England and Wales. Methods: 1054 clinical specimens, which had been confirmed as chlamydia positive (using an nvCT unaffected platform) at nine different diagnostic laboratories throughout England and Wales, were examined for the presence of the 377bp nvCT deletion. Results: 92% (968/1054) of specimens examined were confirmed as wild-type C. trachomatis. The remaining 86 specimens were found to be untypeable, which was probably due to low levels of DNA. No nvCT specimens were identified. Conclusions: There is currently no evidence that nvCT is present in England and Wales; however, laboratories using nvCT-affected platform should remain vigilant.

Original languageEnglish
Pages (from-to)74-75
Number of pages2
JournalSexual Health
Issue number1
Publication statusPublished - 2011


  • Swedish mutant
  • nvCT


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