TY - JOUR
T1 - Sporadic cryptosporidiosis, North Cumbria, England, 1996-2000
AU - Goh, Stella
AU - Reacher, Mark
AU - Casemore, David P.
AU - Verlander, Neville Q.
AU - Chalmers, Rachel
AU - Knowles, Margaret
AU - Williams, Joy
AU - Osborn, Keith
AU - Richards, Sarah
PY - 2004/6
Y1 - 2004/6
N2 - Risk factors for sporadic cryptosporidiosis were determined in 152 patients and 466 unmatched controls who resided in two local government districts in North Cumbria, North West England, from March 1, 1996, to February 29, 2000. Risk was associated with the usual daily volume of cold unboiled tap water drunk (odds ratio [OR] 1.40, 95% confidence intervals [CI] 1.14 to 1.71 per pint consumed per day [p = 0.001]) and short visits to farms (OR 2.02, 95% CI 1.04 to 3.90, p = 0.04). Fifty-six (84%) of 67 fecal specimens from patients obtained from January 1, 1998, and February 29, 2000, were Cryptosporidium parvum genotype 2 (animal and human strain). Livestock fecal pollution of water sources appears to be the leading cause of human sporadic cryptosporidiosis in this population and shows the need for better protection of water catchments from livestock and improved drinking water treatment in this area of England.
AB - Risk factors for sporadic cryptosporidiosis were determined in 152 patients and 466 unmatched controls who resided in two local government districts in North Cumbria, North West England, from March 1, 1996, to February 29, 2000. Risk was associated with the usual daily volume of cold unboiled tap water drunk (odds ratio [OR] 1.40, 95% confidence intervals [CI] 1.14 to 1.71 per pint consumed per day [p = 0.001]) and short visits to farms (OR 2.02, 95% CI 1.04 to 3.90, p = 0.04). Fifty-six (84%) of 67 fecal specimens from patients obtained from January 1, 1998, and February 29, 2000, were Cryptosporidium parvum genotype 2 (animal and human strain). Livestock fecal pollution of water sources appears to be the leading cause of human sporadic cryptosporidiosis in this population and shows the need for better protection of water catchments from livestock and improved drinking water treatment in this area of England.
UR - http://www.scopus.com/inward/record.url?scp=2542625324&partnerID=8YFLogxK
U2 - 10.3201/10.3201/eid1006.030325
DO - 10.3201/10.3201/eid1006.030325
M3 - Article
C2 - 15207050
AN - SCOPUS:2542625324
SN - 1080-6040
VL - 10
SP - 1007
EP - 1015
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 6
ER -
