Sporadic cryptosporidiosis decline after membrane filtration of public water supplies, England, 1996-2002

Stella Goh, Mark Reacher*, David P. Casemore, Neville Q. Verlander, André Charlett, Rachel M. Chalmers, Margaret Knowles, Anthony Pennington, Joy Williams, Keith Osborn, Sarah Richards

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)

Abstract

The incidence of sporadic cryptosporidiosis among 106,000 residents of 2 local government districts in north-west England before and after installation of membrane filtration of public water supplies was compared to that of 59,700 residents whose public water supplies remained unchanged. A national outbreak of foot and mouth disease in livestock during 2001 was associated with a decline in sporadic human cryptosporidiosis in all regions of the United Kingdom. In a Poisson regression model, membrane filtration was associated with an estimated 79% reduction (incidence ratio 0.207, 95% confidence intervals 0.099-0.431, p < 0.0001) after adjustment for the interval of the foot and mouth disease epidemic and the water source. Despite the confounding effect of that epidemic, membrane filtration of the public water supply was effective in reducing the risk for sporadic human Cryptosporidium infection in this population.

Original languageEnglish
Pages (from-to)251-259
Number of pages9
JournalEmerging Infectious Diseases
Volume11
Issue number2
DOIs
Publication statusPublished - Feb 2005

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