TY - JOUR
T1 - Sporadic cryptosporidiosis decline after membrane filtration of public water supplies, England, 1996-2002
AU - Goh, Stella
AU - Reacher, Mark
AU - Casemore, David P.
AU - Verlander, Neville Q.
AU - Charlett, André
AU - Chalmers, Rachel M.
AU - Knowles, Margaret
AU - Pennington, Anthony
AU - Williams, Joy
AU - Osborn, Keith
AU - Richards, Sarah
PY - 2005/2
Y1 - 2005/2
N2 - The incidence of sporadic cryptosporidiosis among 106,000 residents of 2 local government districts in north-west England before and after installation of membrane filtration of public water supplies was compared to that of 59,700 residents whose public water supplies remained unchanged. A national outbreak of foot and mouth disease in livestock during 2001 was associated with a decline in sporadic human cryptosporidiosis in all regions of the United Kingdom. In a Poisson regression model, membrane filtration was associated with an estimated 79% reduction (incidence ratio 0.207, 95% confidence intervals 0.099-0.431, p < 0.0001) after adjustment for the interval of the foot and mouth disease epidemic and the water source. Despite the confounding effect of that epidemic, membrane filtration of the public water supply was effective in reducing the risk for sporadic human Cryptosporidium infection in this population.
AB - The incidence of sporadic cryptosporidiosis among 106,000 residents of 2 local government districts in north-west England before and after installation of membrane filtration of public water supplies was compared to that of 59,700 residents whose public water supplies remained unchanged. A national outbreak of foot and mouth disease in livestock during 2001 was associated with a decline in sporadic human cryptosporidiosis in all regions of the United Kingdom. In a Poisson regression model, membrane filtration was associated with an estimated 79% reduction (incidence ratio 0.207, 95% confidence intervals 0.099-0.431, p < 0.0001) after adjustment for the interval of the foot and mouth disease epidemic and the water source. Despite the confounding effect of that epidemic, membrane filtration of the public water supply was effective in reducing the risk for sporadic human Cryptosporidium infection in this population.
UR - http://www.scopus.com/inward/record.url?scp=13744258078&partnerID=8YFLogxK
U2 - 10.3201/eid1102.040274
DO - 10.3201/eid1102.040274
M3 - Article
C2 - 15752443
AN - SCOPUS:13744258078
SN - 1080-6040
VL - 11
SP - 251
EP - 259
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 2
ER -
