TY - JOUR
T1 - Serotype dynamics of invasive pneumococcal disease post-PCV7 and pre-PCV13 introduction in North East England
AU - Chapman, K. E.
AU - Wilson, D.
AU - Gorton, Russell
PY - 2013/2
Y1 - 2013/2
N2 - The 7-valent pneumococcal conjugate vaccine (PCV7) has been included in the routine childhood immunization programme in the UK since September 2006. A population-based study of serotypes causing invasive pneumococcal disease (IPD) post-PCV7 in North East England was conducted using data from a regional enhanced IPD surveillance system. Overall, there was a 20% reduction [95% confidence interval (CI) 5-32] from 12·1 cases/100 000 population in 2006/2007 to 9·7 in 2009/2010. There was a fall in IPD caused by PCV7 serotypes in all age groups, with reductions of 90% (95% CI 61-99) in children aged <5 years, 50% (95% CI 4-75) in persons aged 5-64 years and 66% (95% CI 40-82) in adults aged
AB - The 7-valent pneumococcal conjugate vaccine (PCV7) has been included in the routine childhood immunization programme in the UK since September 2006. A population-based study of serotypes causing invasive pneumococcal disease (IPD) post-PCV7 in North East England was conducted using data from a regional enhanced IPD surveillance system. Overall, there was a 20% reduction [95% confidence interval (CI) 5-32] from 12·1 cases/100 000 population in 2006/2007 to 9·7 in 2009/2010. There was a fall in IPD caused by PCV7 serotypes in all age groups, with reductions of 90% (95% CI 61-99) in children aged <5 years, 50% (95% CI 4-75) in persons aged 5-64 years and 66% (95% CI 40-82) in adults aged
KW - Invasive pneumococcal disease
KW - Streptococcus pneumoniae (pneumococcus)
KW - pneumococcal conjugate vaccine
UR - http://www.scopus.com/inward/record.url?scp=84876896959&partnerID=8YFLogxK
U2 - 10.1017/S0950268812000763
DO - 10.1017/S0950268812000763
M3 - Article
C2 - 22564258
AN - SCOPUS:84876896959
VL - 141
SP - 344
EP - 352
JO - Epidemiology and Infection
JF - Epidemiology and Infection
SN - 0950-2688
IS - 2
ER -
