Risks of circulatory diseases among Mayak PA workers with radiation doses estimated using the improved Mayak Worker Dosimetry System 2008

Maria B. Moseeva, Tamara V. Azizova*, Evgenia S. Grigoryeva, Richard Haylock

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

The new Mayak Worker Dosimetry System 2008 (MWDS-2008) was published in 2013 and supersedes the Doses-2005 dosimetry system for Mayak Production Association (PA) workers. It provides revised external and internal dose estimates based on the updated occupational history data. Using MWDS-2008, a cohort of 18,856 workers first employed at one of the main Mayak PA plants during 1948-1972 and followed up to 2005 was identified. Incidence and mortality risks from ischemic heart disease (IHD) (International Classification of Diseases (ICD)-9 codes 410-414) and from cerebrovascular diseases (CVD) (ICD-9 codes 430-438) were examined in this cohort and compared with previously published risk estimates in the same cohort based on the Doses-2005 dosimetry system. Significant associations were observed between doses from external gamma-rays and IHD and CVD incidence and also between internal doses from alpha-radiation and IHD mortality and CVD incidence. The estimates of excess relative risk (ERR)/Gy were consistent with those estimates from the previous studies based on Doses-2005 system apart from the relationship between CVD incidence and internal liver dose where the ERR/Gy based on MWDS-2008 was just over three times higher than the corresponding estimate based on Doses-2005 system. Adjustment for smoking status did not show any effect on the estimates of risk from internal alpha-particle exposure.

Original languageEnglish
Pages (from-to)469-477
Number of pages9
JournalRadiation and Environmental Biophysics
Volume53
Issue number2
DOIs
Publication statusPublished - May 2014

Bibliographical note

Funding Information:
Acknowledgments This work was supported in part by the European Commission of the 7 Framework Program under the SOLO project (Epidemiological Studies of Exposed Southern Urals Populations) [Grant Agreement No: 249675].

Keywords

  • Cerebrovascular diseases
  • External gamma-ray exposure
  • Internal alpha-particle exposure
  • Ischemic heart disease
  • Mayak PA
  • Smoking
  • Workers

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