TY - JOUR
T1 - Rising population cost for treating people living with HIV in the UK, 1997-2013
AU - Mandalia, Sundhiya
AU - Mandalia, Roshni
AU - Lo, Gary
AU - Chadborn, Tim
AU - Sharott, Peter
AU - Youle, Mike
AU - Anderson, Jane
AU - Baily, Guy
AU - Brettle, Ray
AU - Fisher, Martin
AU - Gompels, Mark
AU - Kinghorn, George
AU - Johnson, Margaret
AU - McCarron, Brendan
AU - Pozniak, Anton
AU - Tang, Alan
AU - Walsh, John
AU - White, David
AU - Williams, Ian
AU - Gazzard, Brian
AU - Beck, Eduard J.
N1 - Funding Information:
During 2008/2009, the NPMS-HHC was financially supported through a non-restrictive grant from Tibotec, with no influence on the independence of the Steering Group and its editorial policy. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
PY - 2010
Y1 - 2010
N2 - Background: The number of people living with HIV (PLHIV) is increasing in the UK. This study estimated the annual population cost of providing HIV services in the UK, 1997-2006 and projected them 2007-2013. Methods: Annual cost of HIV treatment for PLHIV by stage of HIV infection and type of ART was calculated (UK pounds, 2006 prices). Population costs were derived by multiplying the number of PLHIV by their annual cost for 1997-2006 and projected 2007-2013. Results: Average annual treatment costs across all stages of HIV infection ranged from £17,034 in 1997 to £18,087 in 2006 for PLHIV on mono-therapy and from £27,649 in 1997 to £32,322 in 2006 for those on quadruple-or-more ART. The number of PLHIV using NHS services rose from 16,075 to 52,083 in 2006 and was projected to increase to 78,370 by 2013. Annual population cost rose from £104 million in 1997 to £483 million in 2006, with a projected annual cost between £721 and £758 million by 2013. When including community care costs, costs increased from £164 million in 1997, to £683 million in 2006 and between £1,019 and £1,065 million in 2013. Conclusions: Increased number of PLHIV using NHS services resulted in rising UK population costs. Population costs are expected to continue to increase, partly due to PLHIV's longer survival on ART and the relative lack of success of HIV preventing programs. Where possible, the cost of HIV treatment and care needs to be reduced without reducing the quality of services, and prevention programs need to become more effective. While high income countries are struggling to meet these increasing costs, middle- and lower-income countries with larger epidemics are likely to find it even more difficult to meet these increasing demands, given that they have fewer resources.
AB - Background: The number of people living with HIV (PLHIV) is increasing in the UK. This study estimated the annual population cost of providing HIV services in the UK, 1997-2006 and projected them 2007-2013. Methods: Annual cost of HIV treatment for PLHIV by stage of HIV infection and type of ART was calculated (UK pounds, 2006 prices). Population costs were derived by multiplying the number of PLHIV by their annual cost for 1997-2006 and projected 2007-2013. Results: Average annual treatment costs across all stages of HIV infection ranged from £17,034 in 1997 to £18,087 in 2006 for PLHIV on mono-therapy and from £27,649 in 1997 to £32,322 in 2006 for those on quadruple-or-more ART. The number of PLHIV using NHS services rose from 16,075 to 52,083 in 2006 and was projected to increase to 78,370 by 2013. Annual population cost rose from £104 million in 1997 to £483 million in 2006, with a projected annual cost between £721 and £758 million by 2013. When including community care costs, costs increased from £164 million in 1997, to £683 million in 2006 and between £1,019 and £1,065 million in 2013. Conclusions: Increased number of PLHIV using NHS services resulted in rising UK population costs. Population costs are expected to continue to increase, partly due to PLHIV's longer survival on ART and the relative lack of success of HIV preventing programs. Where possible, the cost of HIV treatment and care needs to be reduced without reducing the quality of services, and prevention programs need to become more effective. While high income countries are struggling to meet these increasing costs, middle- and lower-income countries with larger epidemics are likely to find it even more difficult to meet these increasing demands, given that they have fewer resources.
UR - http://www.scopus.com/inward/record.url?scp=78651260635&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0015677
DO - 10.1371/journal.pone.0015677
M3 - Article
C2 - 21209893
AN - SCOPUS:78651260635
SN - 1932-6203
VL - 5
JO - PLoS ONE
JF - PLoS ONE
IS - 12
M1 - e15677
ER -