Response to hepatitis-B vaccination in healthy homosexual individuals: Retrospective case control study

Satyajit Das*, Mary Brassington, Susan M. Drake, Elizabeth Boxall

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)

    Abstract

    The aim of the study was to compare the responses of homosexual men (HM) receiving a standard course of recombinant hepatitis B vaccine with those of healthcare workers vaccinated in the same hospital over the same period. Boosters for inadequate responders and repeat courses for non-responders were given. Forty of 61 (75.4%) of HM completing full follow-up were successfully vaccinated, compared with 128 of 129 (99.2%) female and 94 of 96 (97.9%) male health care workers (P<0.001). The response to hepatitis-B vaccination in healthy homosexual men is poor and significantly lower than healthcare workers vaccinated and followed up according to the same protocol.

    Original languageEnglish
    Pages (from-to)3701-3705
    Number of pages5
    JournalVaccine
    Volume21
    Issue number25-26
    DOIs
    Publication statusPublished - 2003

    Keywords

    • Case control study
    • Hepatitis-B vaccination
    • Homosexual individuals

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