Reliability of the ICRP's dose coefficients for members of the public: IV. Basis of the human alimentary tract model and uncertainties in model predictions

R. Leggett*, J. Harrison, A. Phipps

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    15 Citations (Scopus)

    Abstract

    The biokinetic and dosimetric model of the gastrointestinal (GI) tract applied in current documents of the International Commission on Radiological Protection (ICRP) was developed in the mid-1960s. The model was based on features of a reference adult male and was first used by the ICRP in Publication 30, Limits for Intakes of Radionuclides by Workers (Part 1, 1979). In the late 1990s an ICRP task group was appointed to develop a biokinetic and dosimetric model of the alimentary tract that reflects updated information and addresses current needs in radiation protection. The new age-specific and gender-specific model, called the Human Alimentary Tract Model (HATM), has been completed and will replace the GI model of Publication 30 in upcoming ICRP documents. This paper discusses the basis for the structure and parameter values of the HATM, summarises the uncertainties associated with selected features and types of predictions of the HATM and examines the sensitivity of dose estimates to these uncertainties for selected radionuclides. Emphasis is on generic biokinetic features of the HATM, particularly transit times through the lumen of the alimentary tract, but key dosimetric features of the model are outlined, and the sensitivity of tissue dose estimates to uncertainties in dosimetric as well as biokinetic features of the HATM are examined for selected radionuclides.

    Original languageEnglish
    Pages (from-to)156-170
    Number of pages15
    JournalRadiation Protection Dosimetry
    Volume123
    Issue number2
    DOIs
    Publication statusPublished - Feb 2007

    Bibliographical note

    Funding Information:
    The model addressed in this paper was developed by a task group of the International Commission on Radiological Protection. Members of the task group were H. Métivier, (chairman), J. Bertholon, J. Harrison, J. Hendry, R. Leggett, D, Melo, D. Nosske, A. Phipps, F. Paquet, M. Simko, and R. Thomas. The work of the first author in the preparation of this paper was supported in part by Contract WF6970Y1 with the U.S. Nuclear Regulatory Commission, Office of Nuclear Regulatory Research, Division of System Analysis and Regulatory Effectiveness (Dr. Robert A. Meck, Project Officer) through Interagency Agreement 41W6970Y1 with the U.S. Department of Energy (DOE).

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