Regression of AIDS-related Kaposi's sarcoma during therapy with thalidomide

Rolf A. Solèr; Mark Howard; Nicola S. Brink; Diana Gibb; Richard Tedder; David Nadal

doi:10.1093/clinids/23.3.501

Regression of AIDS-related Kaposi's sarcoma during therapy with thalidomide

Rolf A. Solèr, Mark Howard, Nicola S. Brink, Diana Gibb, Richard Tedder, David Nadal^*

^*Corresponding author for this work

Public Health England

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70 Citations (Scopus)

Abstract

A 14-year-old girl with HIV infection and subcutaneous Kaposi's sarcoma (KS) received thalidomide therapy for oral ulcers, resulting in regression of KS lesions, disappearance of KS-associated herpesvirus (KSHV) DNA from blood, and reduced viral load in tumor tissue. Administration of granulocyte colony- stimulating factor resulted in clinical exacerbation of KS add reappearance of KSHV DNA in blood.

Original language	English
Pages (from-to)	501-505
Number of pages	5
Journal	Clinical Infectious Diseases
Volume	23
Issue number	3
DOIs	https://doi.org/10.1093/clinids/23.3.501
Publication status	Published - 1996

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10.1093/clinids/23.3.501

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title = "Regression of AIDS-related Kaposi's sarcoma during therapy with thalidomide",

abstract = "A 14-year-old girl with HIV infection and subcutaneous Kaposi's sarcoma (KS) received thalidomide therapy for oral ulcers, resulting in regression of KS lesions, disappearance of KS-associated herpesvirus (KSHV) DNA from blood, and reduced viral load in tumor tissue. Administration of granulocyte colony- stimulating factor resulted in clinical exacerbation of KS add reappearance of KSHV DNA in blood.",

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AU - Tedder, Richard

AU - Nadal, David

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Regression of AIDS-related Kaposi's sarcoma during therapy with thalidomide

Abstract

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