Recurrent epidemic hepatitis a associated with consumption of raw shellfish, probably controlled throfgh public health measures

Alfonso Mele; Maria Grazia Rastelli; Owen Noel Gill; Domenico Di Bisceglie; Francesco Rosmini; Giancarlo Pardelli; Carla Valtriani; Pirluigi Patriarchi

doi:10.1093/oxfordjournals.aje.a115368

Recurrent epidemic hepatitis a associated with consumption of raw shellfish, probably controlled throfgh public health measures

Alfonso Mele^*, Maria Grazia Rastelli, Owen Noel Gill, Domenico Di Bisceglie, Francesco Rosmini, Giancarlo Pardelli, Carla Valtriani, Pirluigi Patriarchi

^*Corresponding author for this work

C-19: HP: Contact Tracing Response

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Abstract

Between April 1984 and January 1985, in the Italian seaport of Livomo, the annual incidence of serologically confirmed acute hepatitis A doubled to 46 per 100,000 population. The exposure histories of each of 75 jaundiced subjects with serologically confirmed hepatitis A were compared with up to four, randomly chosen-, age-, sex-, and neighborhood-matched controls. Illness was strongly associated with consumption of raw mussels and clams within six weeks of onset of illness. When the two thirds of the subjects who had been exposed were classified according to the frequency with which they had recently consumed any type of raw shellfish, there was a clear dose-response relation. In February 1985, comprehensive control measures were introduced and the annual incidence of hepatitis A fell to 2.3 per 100,000 population, a 10-fold decrease from the preepidemic period.

Original language	English
Pages (from-to)	540-546
Number of pages	7
Journal	American Journal of Epidemiology
Volume	130
Issue number	3
DOIs	https://doi.org/10.1093/oxfordjournals.aje.a115368
Publication status	Published - Sep 1989

Bibliographical note

Funding Information:
This continuing surveillance project is partially supported by the Consiglio Nazionale delle Ricerche (Grant no. 84.01899.04). The scientific exchange program with the Communicable Disease Surveillance Centre, London, from which the SEIEVA project emerged, was funded by the British Council, The authors thank Dr. P. Baroncini, Dr. L. Tognazzi, and R. Celanti of the Livorno Public Health Department who gave invaluable assistance with field-work.

Keywords

Food contamination
Hepatitis A
Retrospective studies
Shellfish

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/oxfordjournals.aje.a115368

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title = "Recurrent epidemic hepatitis a associated with consumption of raw shellfish, probably controlled throfgh public health measures",

abstract = "Between April 1984 and January 1985, in the Italian seaport of Livomo, the annual incidence of serologically confirmed acute hepatitis A doubled to 46 per 100,000 population. The exposure histories of each of 75 jaundiced subjects with serologically confirmed hepatitis A were compared with up to four, randomly chosen-, age-, sex-, and neighborhood-matched controls. Illness was strongly associated with consumption of raw mussels and clams within six weeks of onset of illness. When the two thirds of the subjects who had been exposed were classified according to the frequency with which they had recently consumed any type of raw shellfish, there was a clear dose-response relation. In February 1985, comprehensive control measures were introduced and the annual incidence of hepatitis A fell to 2.3 per 100,000 population, a 10-fold decrease from the preepidemic period.",

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note = "Funding Information: This continuing surveillance project is partially supported by the Consiglio Nazionale delle Ricerche (Grant no. 84.01899.04). The scientific exchange program with the Communicable Disease Surveillance Centre, London, from which the SEIEVA project emerged, was funded by the British Council, The authors thank Dr. P. Baroncini, Dr. L. Tognazzi, and R. Celanti of the Livorno Public Health Department who gave invaluable assistance with field-work.",

year = "1989",

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doi = "10.1093/oxfordjournals.aje.a115368",

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AU - Mele, Alfonso

AU - Rastelli, Maria Grazia

AU - Gill, Owen Noel

AU - Bisceglie, Domenico Di

AU - Rosmini, Francesco

AU - Pardelli, Giancarlo

AU - Valtriani, Carla

AU - Patriarchi, Pirluigi

N1 - Funding Information: This continuing surveillance project is partially supported by the Consiglio Nazionale delle Ricerche (Grant no. 84.01899.04). The scientific exchange program with the Communicable Disease Surveillance Centre, London, from which the SEIEVA project emerged, was funded by the British Council, The authors thank Dr. P. Baroncini, Dr. L. Tognazzi, and R. Celanti of the Livorno Public Health Department who gave invaluable assistance with field-work.

PY - 1989/9

Y1 - 1989/9

N2 - Between April 1984 and January 1985, in the Italian seaport of Livomo, the annual incidence of serologically confirmed acute hepatitis A doubled to 46 per 100,000 population. The exposure histories of each of 75 jaundiced subjects with serologically confirmed hepatitis A were compared with up to four, randomly chosen-, age-, sex-, and neighborhood-matched controls. Illness was strongly associated with consumption of raw mussels and clams within six weeks of onset of illness. When the two thirds of the subjects who had been exposed were classified according to the frequency with which they had recently consumed any type of raw shellfish, there was a clear dose-response relation. In February 1985, comprehensive control measures were introduced and the annual incidence of hepatitis A fell to 2.3 per 100,000 population, a 10-fold decrease from the preepidemic period.

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Recurrent epidemic hepatitis a associated with consumption of raw shellfish, probably controlled throfgh public health measures

Abstract

Bibliographical note

Keywords

UN SDGs

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