Recombination Analysis Tool (RAT): A program for the high-throughput detection of recombination

Graham J. Etherington; Jo Dicks; Ian N. Roberts

doi:10.1093/bioinformatics/bth500

Recombination Analysis Tool (RAT): A program for the high-throughput detection of recombination

Graham J. Etherington^*, Jo Dicks, Ian N. Roberts

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

95 Citations (Scopus)

Abstract

Motivation: Recombination can be a prevailing drive in shaping genome evolution. RAT (Recombination Analysis Tool) is a Java-based tool for investigating recombination events in any number of aligned sequences (protein or DNA) of any length (short viral sequences to full genomes). It is an uncomplicated and intuitive application and allows the user to view only the regions of sequence alignments they are interested in. Results: RAT was applied to viral sequences. Its utility was demonstrated through the detection of a known recombinant of HIV and a detailed analysis of Noroviruses, the most common cause of viral gastroenteritis in humans.

Original language	English
Pages (from-to)	278-281
Number of pages	4
Journal	Bioinformatics
Volume	21
Issue number	3
DOIs	https://doi.org/10.1093/bioinformatics/bth500
Publication status	Published - 1 Feb 2005
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by a grant from the Biotechnology and Biological Sciences Research Council.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/bioinformatics/bth500

Cite this

@article{724170b3b8ef469d8b8cc5c546003429,

title = "Recombination Analysis Tool (RAT): A program for the high-throughput detection of recombination",

abstract = "Motivation: Recombination can be a prevailing drive in shaping genome evolution. RAT (Recombination Analysis Tool) is a Java-based tool for investigating recombination events in any number of aligned sequences (protein or DNA) of any length (short viral sequences to full genomes). It is an uncomplicated and intuitive application and allows the user to view only the regions of sequence alignments they are interested in. Results: RAT was applied to viral sequences. Its utility was demonstrated through the detection of a known recombinant of HIV and a detailed analysis of Noroviruses, the most common cause of viral gastroenteritis in humans.",

author = "Etherington, {Graham J.} and Jo Dicks and Roberts, {Ian N.}",

note = "Funding Information: This work was supported by a grant from the Biotechnology and Biological Sciences Research Council.",

year = "2005",

month = feb,

day = "1",

doi = "10.1093/bioinformatics/bth500",

language = "English",

volume = "21",

pages = "278--281",

journal = "Bioinformatics",

issn = "1367-4803",

publisher = "Oxford University Press",

number = "3",

}

TY - JOUR

T1 - Recombination Analysis Tool (RAT)

T2 - A program for the high-throughput detection of recombination

AU - Etherington, Graham J.

AU - Dicks, Jo

AU - Roberts, Ian N.

N1 - Funding Information: This work was supported by a grant from the Biotechnology and Biological Sciences Research Council.

PY - 2005/2/1

Y1 - 2005/2/1

N2 - Motivation: Recombination can be a prevailing drive in shaping genome evolution. RAT (Recombination Analysis Tool) is a Java-based tool for investigating recombination events in any number of aligned sequences (protein or DNA) of any length (short viral sequences to full genomes). It is an uncomplicated and intuitive application and allows the user to view only the regions of sequence alignments they are interested in. Results: RAT was applied to viral sequences. Its utility was demonstrated through the detection of a known recombinant of HIV and a detailed analysis of Noroviruses, the most common cause of viral gastroenteritis in humans.

AB - Motivation: Recombination can be a prevailing drive in shaping genome evolution. RAT (Recombination Analysis Tool) is a Java-based tool for investigating recombination events in any number of aligned sequences (protein or DNA) of any length (short viral sequences to full genomes). It is an uncomplicated and intuitive application and allows the user to view only the regions of sequence alignments they are interested in. Results: RAT was applied to viral sequences. Its utility was demonstrated through the detection of a known recombinant of HIV and a detailed analysis of Noroviruses, the most common cause of viral gastroenteritis in humans.

UR - http://www.scopus.com/inward/record.url?scp=13844275303&partnerID=8YFLogxK

U2 - 10.1093/bioinformatics/bth500

DO - 10.1093/bioinformatics/bth500

M3 - Article

C2 - 15333462

AN - SCOPUS:13844275303

SN - 1367-4803

VL - 21

SP - 278

EP - 281

JO - Bioinformatics

JF - Bioinformatics

IS - 3

ER -

Recombination Analysis Tool (RAT): A program for the high-throughput detection of recombination

Abstract

Bibliographical note

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this