Radioiodination of myoglobin with 125I using an on-line solid phase HPLC-coupled procedure

Gy Szabó; Robert Bulman; Katalin Offenmüller

doi:10.1016/0883-2889(91)90167-Y

Radioiodination of myoglobin with ¹²⁵I using an on-line solid phase HPLC-coupled procedure

Gy Szabó^*, Robert Bulman, Katalin Offenmüller

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

A new procedure is described for the radioiodination of proteins, such as myoglobin, which carry sensitive moieties, such as thiols or porphyrins. Myoglobin has been iodinated with ¹²⁵I by using the iodinating reagent, IODO-GEN^R, which has been adsorbed onto polyol silica and packed in a reactor pre-column coupled in tandem to a gel permeation chromatography column.

Original language	English
Pages (from-to)	585-586
Number of pages	2
Journal	International Journal of Radiation Applications and Instrumentation. Part
Volume	42
Issue number	6
DOIs	https://doi.org/10.1016/0883-2889(91)90167-Y
Publication status	Published - 1991

Bibliographical note

Funding Information:
AcknowledgemenrPThis study was initiated under the auspices of the International Atomic Energy Agency who provided a research fellowship for Gy. Szabo. This support is acknowledged with gratitude.

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title = "Radioiodination of myoglobin with 125I using an on-line solid phase HPLC-coupled procedure",

abstract = "A new procedure is described for the radioiodination of proteins, such as myoglobin, which carry sensitive moieties, such as thiols or porphyrins. Myoglobin has been iodinated with 125I by using the iodinating reagent, IODO-GENR, which has been adsorbed onto polyol silica and packed in a reactor pre-column coupled in tandem to a gel permeation chromatography column.",

author = "Gy Szab{\'o} and Robert Bulman and Katalin Offenm{\"u}ller",

note = "Funding Information: AcknowledgemenrPThis study was initiated under the auspices of the International Atomic Energy Agency who provided a research fellowship for Gy. Szabo. This support is acknowledged with gratitude.",

year = "1991",

doi = "10.1016/0883-2889(91)90167-Y",

language = "English",

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pages = "585--586",

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T1 - Radioiodination of myoglobin with 125I using an on-line solid phase HPLC-coupled procedure

AU - Szabó, Gy

AU - Bulman, Robert

AU - Offenmüller, Katalin

N1 - Funding Information: AcknowledgemenrPThis study was initiated under the auspices of the International Atomic Energy Agency who provided a research fellowship for Gy. Szabo. This support is acknowledged with gratitude.

PY - 1991

Y1 - 1991

N2 - A new procedure is described for the radioiodination of proteins, such as myoglobin, which carry sensitive moieties, such as thiols or porphyrins. Myoglobin has been iodinated with 125I by using the iodinating reagent, IODO-GENR, which has been adsorbed onto polyol silica and packed in a reactor pre-column coupled in tandem to a gel permeation chromatography column.

AB - A new procedure is described for the radioiodination of proteins, such as myoglobin, which carry sensitive moieties, such as thiols or porphyrins. Myoglobin has been iodinated with 125I by using the iodinating reagent, IODO-GENR, which has been adsorbed onto polyol silica and packed in a reactor pre-column coupled in tandem to a gel permeation chromatography column.

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U2 - 10.1016/0883-2889(91)90167-Y

DO - 10.1016/0883-2889(91)90167-Y

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C2 - 1652581

AN - SCOPUS:0026085185

SN - 0883-2889

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JO - International Journal of Radiation Applications and Instrumentation. Part

JF - International Journal of Radiation Applications and Instrumentation. Part

IS - 6

ER -

Radioiodination of myoglobin with ¹²⁵I using an on-line solid phase HPLC-coupled procedure

Abstract

Bibliographical note

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