Prospective study of the burden of rotavirus gastroenteritis in Danish children and their families

Thomas Hoffmann*, Miren Iturriza-Go'Mara, Jens Faaborg-Andersen, Christina Kraaer, Christina P. Nielsen, James Gray, Birthe Hogh

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


This was the first study to characterize the total burden of rotavirus gastroenteritis (RVGE) at both hospital and general physician (GP) clinics in Denmark, and also the first to confirm rotavirus (RV) as the leading cause of acute gastroenteritis (GE) among children <5 years in GP clinics nationwide. Several aspects of RVGE were reported, including the impact of RVGE on family life by changes in HRQoL and by the number of days absent from day care. RV was detected in 225 (63.6%) children, and the median number of days absent from day care was 5 days. In 43.0% of the families, at least one family member, a total of 170 individuals, experienced symptoms of acute GE. Reduced health-related quality of life was observed both among children and parents. Our data suggested that RVGE indirectly as well as directly is a major public health burden in Denmark and comparable with data from other European countries.

Original languageEnglish
Pages (from-to)1535-1539
Number of pages5
JournalEuropean Journal of Pediatrics
Issue number12
Publication statusPublished - Dec 2011

Bibliographical note

Funding Information:
Acknowledgments The authors would like to thank all investigators and study nurses for participating in this study and Sanofi Pasteur MSD ApS, Denmark for financial support. Data collection was done by the investigators. Data processing was performed by an independent CRO.

Copyright 2012 Elsevier B.V., All rights reserved.


  • Child
  • Denmark
  • Gastroenteritis
  • Quality of life
  • Rotavirus


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