Primary investigation of 31 infants with suspected congenital rubella syndrome in Sudan

A. Omer, E. H. Abdel Rahim, E. E. Ali, Li Jin*

*Corresponding author for this work

Research output: Contribution to journalComment/debate

14 Citations (Scopus)

Abstract

Between 2005 and 2006, clinical specimens were collected from 31 infants with suspected congenital rubella syndrome (CRS) who presented at six hospitals in Khartoum, Sudan. Eleven (35.5%) were laboratory confirmed as CRS cases by testing for anti-rubella IgM, IgG and viral genome. For the first time in Sudan, the rubella virus genome was directly detected in clinical specimens of six CRS cases and two viruses were isolated in cell culture. Phylogenetic analysis suggested that three genotypes of rubella virus (RV; 1E, 2B and 1G) were co-circulating in Sudan. The study introduced the methodology for CRS confirmation and surveillance in Sudan and provides preliminary data.

Original languageEnglish
Pages (from-to)678-682
Number of pages5
JournalClinical Microbiology and Infection
Volume16
Issue number6
DOIs
Publication statusPublished - Jun 2010

Bibliographical note

Funding Information:
This work was supported by the UNESCO-IUMS-SGM short-term fellowship. The award was for travel, housing and meal expenses, besides the support from the National Centre for Research, Khartoum, Sudan. The authors declare no conflict of interest.

Keywords

  • Congenital rubella syndrome
  • Genotyping
  • Rubella virus
  • Sudan
  • Virus isolation

Fingerprint

Dive into the research topics of 'Primary investigation of 31 infants with suspected congenital rubella syndrome in Sudan'. Together they form a unique fingerprint.

Cite this