Prevention of perinatal transmission of hepatitis B to babies at high risk: An evaluation

David Sloan; Mary Ramsay; Leonie Prasad; David Gelb; Chong Gee Teo

doi:10.1016/j.vaccine.2005.07.040

Prevention of perinatal transmission of hepatitis B to babies at high risk: An evaluation

David Sloan, Mary Ramsay^*, Leonie Prasad, David Gelb, Chong Gee Teo

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

We aimed to determine factors associated with successful vaccination coverage and development of infection in high-risk infants born to hepatitis B infected women. Immunisation of 860/932 (92%) of babies was started within 48 h of birth and three doses of vaccination completed for 794/921 (86%). Only 543 (58%) infants were tested and 26 (4.9%) were found to have evidence of current infection. Delayed start of immunisation was significantly associated with unbooked pregnancy, maternal hepatitis B e-markers and year. Current infection in the baby was strongly associated with maternal hepatitis B e-status, ethnicity and year of vaccination. The proportion of infants developing infection declined after 1998, coinciding with the publication of national recommendations and the wider use of the accelerated schedule.

Original language	English
Pages (from-to)	5500-5508
Number of pages	9
Journal	Vaccine
Volume	23
Issue number	48-49
DOIs	https://doi.org/10.1016/j.vaccine.2005.07.040
Publication status	Published - 1 Dec 2005

Keywords

Evaluation
Hepatitis B
Immunisation
Neonatal
Vertical transmission

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.vaccine.2005.07.040

Cite this

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title = "Prevention of perinatal transmission of hepatitis B to babies at high risk: An evaluation",

abstract = "We aimed to determine factors associated with successful vaccination coverage and development of infection in high-risk infants born to hepatitis B infected women. Immunisation of 860/932 (92%) of babies was started within 48 h of birth and three doses of vaccination completed for 794/921 (86%). Only 543 (58%) infants were tested and 26 (4.9%) were found to have evidence of current infection. Delayed start of immunisation was significantly associated with unbooked pregnancy, maternal hepatitis B e-markers and year. Current infection in the baby was strongly associated with maternal hepatitis B e-status, ethnicity and year of vaccination. The proportion of infants developing infection declined after 1998, coinciding with the publication of national recommendations and the wider use of the accelerated schedule.",

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T1 - Prevention of perinatal transmission of hepatitis B to babies at high risk

T2 - An evaluation

AU - Sloan, David

AU - Ramsay, Mary

AU - Prasad, Leonie

AU - Gelb, David

AU - Teo, Chong Gee

PY - 2005/12/1

Y1 - 2005/12/1

N2 - We aimed to determine factors associated with successful vaccination coverage and development of infection in high-risk infants born to hepatitis B infected women. Immunisation of 860/932 (92%) of babies was started within 48 h of birth and three doses of vaccination completed for 794/921 (86%). Only 543 (58%) infants were tested and 26 (4.9%) were found to have evidence of current infection. Delayed start of immunisation was significantly associated with unbooked pregnancy, maternal hepatitis B e-markers and year. Current infection in the baby was strongly associated with maternal hepatitis B e-status, ethnicity and year of vaccination. The proportion of infants developing infection declined after 1998, coinciding with the publication of national recommendations and the wider use of the accelerated schedule.

AB - We aimed to determine factors associated with successful vaccination coverage and development of infection in high-risk infants born to hepatitis B infected women. Immunisation of 860/932 (92%) of babies was started within 48 h of birth and three doses of vaccination completed for 794/921 (86%). Only 543 (58%) infants were tested and 26 (4.9%) were found to have evidence of current infection. Delayed start of immunisation was significantly associated with unbooked pregnancy, maternal hepatitis B e-markers and year. Current infection in the baby was strongly associated with maternal hepatitis B e-status, ethnicity and year of vaccination. The proportion of infants developing infection declined after 1998, coinciding with the publication of national recommendations and the wider use of the accelerated schedule.

KW - Evaluation

KW - Hepatitis B

KW - Immunisation

KW - Neonatal

KW - Vertical transmission

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DO - 10.1016/j.vaccine.2005.07.040

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SN - 0264-410X

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EP - 5508

JO - Vaccine

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IS - 48-49

ER -

Prevention of perinatal transmission of hepatitis B to babies at high risk: An evaluation

Abstract

Keywords

UN SDGs

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