Pooled testing for SARS-CoV-2 in hospitalized patients

David Mastrianni; Richard Falivena; Timothy Brooks; Brian McDermott; Josenia Tan; Richard Vandell; Michael Holland

doi:10.12788/jhm.3501

Pooled testing for SARS-CoV-2 in hospitalized patients

David Mastrianni^*, Richard Falivena, Timothy Brooks, Brian McDermott, Josenia Tan, Richard Vandell, Michael Holland

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Viral testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly early in the COVID-19 pandemic, was limited by supply of reagents. We pooled nasopharyngeal samples from patients at low risk of SARS-CoV-2 infection in groups of 3 for testing. Three weeks of testing using this strategy resulted in 530 patient tests in 179 cartridges; 4 positive test groups required the use of 11 additional cartridges with an overall positive rate of 0.8% in a low-risk population. This strategy resulted in the use of 340 fewer cartridges than if each test were performed on one patient sample.

Original language	English
Pages (from-to)	538-539
Number of pages	2
Journal	Journal of Hospital Medicine
Volume	15
Issue number	9
DOIs	https://doi.org/10.12788/jhm.3501
Publication status	Published - Sept 2020
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2020 Society of Hospital Medicine

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title = "Pooled testing for SARS-CoV-2 in hospitalized patients",

abstract = "Viral testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly early in the COVID-19 pandemic, was limited by supply of reagents. We pooled nasopharyngeal samples from patients at low risk of SARS-CoV-2 infection in groups of 3 for testing. Three weeks of testing using this strategy resulted in 530 patient tests in 179 cartridges; 4 positive test groups required the use of 11 additional cartridges with an overall positive rate of 0.8% in a low-risk population. This strategy resulted in the use of 340 fewer cartridges than if each test were performed on one patient sample.",

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AU - Brooks, Timothy

AU - McDermott, Brian

AU - Tan, Josenia

AU - Vandell, Richard

AU - Holland, Michael

PY - 2020/9

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AB - Viral testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly early in the COVID-19 pandemic, was limited by supply of reagents. We pooled nasopharyngeal samples from patients at low risk of SARS-CoV-2 infection in groups of 3 for testing. Three weeks of testing using this strategy resulted in 530 patient tests in 179 cartridges; 4 positive test groups required the use of 11 additional cartridges with an overall positive rate of 0.8% in a low-risk population. This strategy resulted in the use of 340 fewer cartridges than if each test were performed on one patient sample.

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ER -

Pooled testing for SARS-CoV-2 in hospitalized patients

Abstract

Bibliographical note

UN SDGs

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