Pathbase: A new reference resource and database for laboratory mouse pathology

Paul N. Schofield; Jonathan B.L. Bard; Jacques Boniver; Vincenzo Covelli; Philippe Delvenne; Michele Ellender; Wilhelm Engstrom; Wolfgang Goessner; Michael Gruenberger; Heinz Hoefler; John W. Hopewell; Mariateresa Mancuso; Carmel Mothersill; Leticia Quintanilla-Martinez; Bjorn Rozell; Hannu Sariola; John P. Sundberg; Andrew Ward

doi:10.1093/rpd/nch101

Pathbase: A new reference resource and database for laboratory mouse pathology

Paul N. Schofield^*
, Jonathan B.L. Bard
, Jacques Boniver
, Vincenzo Covelli
, Philippe Delvenne
, Michele Ellender
, Wilhelm Engstrom
, Wolfgang Goessner
, Michael Gruenberger
, Heinz Hoefler
, John W. Hopewell
, Mariateresa Mancuso
, Carmel Mothersill
, Leticia Quintanilla-Martinez
, Bjorn Rozell
, Hannu Sariola
, John P. Sundberg
, Andrew Ward

^*Corresponding author for this work

Radiation Effects

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Pathbase (http:/www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies, and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.

Original language	English
Pages (from-to)	525-528
Number of pages	4
Journal	Radiation Protection Dosimetry
Volume	112
Issue number	4
DOIs	https://doi.org/10.1093/rpd/nch101
Publication status	Published - 2004

Bibliographical note

Funding Information:
This work was funded by the European Commission under Contract QLRI-CT-1999-00320. The authors would like to thank Drs Cory Brayton, Jerry Ward, Madhuri Warren, Laurence Fiette and Janan Eppig for their invaluable inputs into the development of MPATH and their support of Pathbase.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1093/rpd/nch101

Cite this

Schofield, P. N., Bard, J. B. L., Boniver, J., Covelli, V., Delvenne, P., Ellender, M., Engstrom, W., Goessner, W., Gruenberger, M., Hoefler, H., Hopewell, J. W., Mancuso, M., Mothersill, C., Quintanilla-Martinez, L., Rozell, B., Sariola, H., Sundberg, J. P., & Ward, A. (2004). Pathbase: A new reference resource and database for laboratory mouse pathology. Radiation Protection Dosimetry, 112(4), 525-528. https://doi.org/10.1093/rpd/nch101

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title = "Pathbase: A new reference resource and database for laboratory mouse pathology",

abstract = "Pathbase (http:/www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies, and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.",

author = "Schofield, \{Paul N.\} and Bard, \{Jonathan B.L.\} and Jacques Boniver and Vincenzo Covelli and Philippe Delvenne and Michele Ellender and Wilhelm Engstrom and Wolfgang Goessner and Michael Gruenberger and Heinz Hoefler and Hopewell, \{John W.\} and Mariateresa Mancuso and Carmel Mothersill and Leticia Quintanilla-Martinez and Bjorn Rozell and Hannu Sariola and Sundberg, \{John P.\} and Andrew Ward",

note = "Funding Information: This work was funded by the European Commission under Contract QLRI-CT-1999-00320. The authors would like to thank Drs Cory Brayton, Jerry Ward, Madhuri Warren, Laurence Fiette and Janan Eppig for their invaluable inputs into the development of MPATH and their support of Pathbase.",

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doi = "10.1093/rpd/nch101",

language = "English",

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Schofield, PN, Bard, JBL, Boniver, J, Covelli, V, Delvenne, P, Ellender, M, Engstrom, W, Goessner, W, Gruenberger, M, Hoefler, H, Hopewell, JW, Mancuso, M, Mothersill, C, Quintanilla-Martinez, L, Rozell, B, Sariola, H, Sundberg, JP & Ward, A 2004, 'Pathbase: A new reference resource and database for laboratory mouse pathology', Radiation Protection Dosimetry, vol. 112, no. 4, pp. 525-528. https://doi.org/10.1093/rpd/nch101

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T2 - A new reference resource and database for laboratory mouse pathology

AU - Schofield, Paul N.

AU - Bard, Jonathan B.L.

AU - Boniver, Jacques

AU - Covelli, Vincenzo

AU - Delvenne, Philippe

AU - Ellender, Michele

AU - Engstrom, Wilhelm

AU - Goessner, Wolfgang

AU - Gruenberger, Michael

AU - Hoefler, Heinz

AU - Hopewell, John W.

AU - Mancuso, Mariateresa

AU - Mothersill, Carmel

AU - Quintanilla-Martinez, Leticia

AU - Rozell, Bjorn

AU - Sariola, Hannu

AU - Sundberg, John P.

AU - Ward, Andrew

N1 - Funding Information: This work was funded by the European Commission under Contract QLRI-CT-1999-00320. The authors would like to thank Drs Cory Brayton, Jerry Ward, Madhuri Warren, Laurence Fiette and Janan Eppig for their invaluable inputs into the development of MPATH and their support of Pathbase.

PY - 2004

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N2 - Pathbase (http:/www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies, and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.

AB - Pathbase (http:/www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies, and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.

UR - https://www.scopus.com/pages/publications/19944430715

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JO - Radiation Protection Dosimetry

JF - Radiation Protection Dosimetry

IS - 4

ER -

Pathbase: A new reference resource and database for laboratory mouse pathology

Abstract

Bibliographical note

UN SDGs

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