Pathbase: A new reference resource and database for laboratory mouse pathology

Paul N. Schofield*, Jonathan B.L. Bard, Jacques Boniver, Vincenzo Covelli, Philippe Delvenne, Michele Ellender, Wilhelm Engstrom, Wolfgang Goessner, Michael Gruenberger, Heinz Hoefler, John W. Hopewell, Mariateresa Mancuso, Carmel Mothersill, Leticia Quintanilla-Martinez, Bjorn Rozell, Hannu Sariola, John P. Sundberg, Andrew Ward

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Pathbase (http:/ is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies, and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.

Original languageEnglish
Pages (from-to)525-528
Number of pages4
JournalRadiation Protection Dosimetry
Issue number4
Publication statusPublished - 2004

Bibliographical note

Funding Information:
This work was funded by the European Commission under Contract QLRI-CT-1999-00320. The authors would like to thank Drs Cory Brayton, Jerry Ward, Madhuri Warren, Laurence Fiette and Janan Eppig for their invaluable inputs into the development of MPATH and their support of Pathbase.


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