Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

Caroline L. Trotter; Jodie McVernon; Mary Ramsay; Cynthia G. Whitney; E. Kim Mulholland; David Goldblatt; Joachim Hombach; Marie Paule Kieny

doi:10.1016/j.vaccine.2008.05.073

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

Caroline L. Trotter^*, Jodie McVernon, Mary Ramsay, Cynthia G. Whitney, E. Kim Mulholland, David Goldblatt, Joachim Hombach, Marie Paule Kieny

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

129 Citations (Scopus)

Abstract

Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines.

Original language	English
Pages (from-to)	4434-4445
Number of pages	12
Journal	Vaccine
Volume	26
Issue number	35
DOIs	https://doi.org/10.1016/j.vaccine.2008.05.073
Publication status	Published - 18 Aug 2008

Keywords

Haemophilus vaccines
Meningococcal vaccines
Pneumococcal vaccines

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.vaccine.2008.05.073

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title = "Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae",

abstract = "Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines.",

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AU - Trotter, Caroline L.

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AU - Ramsay, Mary

AU - Whitney, Cynthia G.

AU - Mulholland, E. Kim

AU - Goldblatt, David

AU - Hombach, Joachim

AU - Kieny, Marie Paule

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AB - Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines.

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KW - Meningococcal vaccines

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Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

Abstract

Keywords

UN SDGs

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