Ongoing outbreak of invasive and non-invasive disease due to group a Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016

Nicholas Bundle; L. Bubba; J. Coelho; R. Kwiatkowska; R. Cloke; S. King; J. Rajan-Iyer; M. Courtney-Pillinger; Charles Beck; V. Hope; Theresa Lamagni; Colin Brown; D. Jermacane; R. Glass; Monica Desai; Maya Gobin; S. Balasegaram; Charlotte Anderson

doi:10.2807/1560-7917.ES.2017.22.3.30446

Ongoing outbreak of invasive and non-invasive disease due to group a Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016

Nicholas Bundle^*, L. Bubba, J. Coelho, R. Kwiatkowska, R. Cloke, S. King, J. Rajan-Iyer, M. Courtney-Pillinger, Charles Beck, V. Hope, Theresa Lamagni, Colin Brown, D. Jermacane, R. Glass, Monica Desai, Maya Gobin, S. Balasegaram, Charlotte Anderson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

We report an outbreak of invasive and non-invasive disease due to an unusual type of Streptococcus pyogenes(group A Streptococcus, emm66) among a vulnerable, largely homeless population in southern England and Wales, detected in September 2016. Twenty-seven confirmed cases were subsequently identified between 5 January and 29 December 2016; 20 injected drugs and six reported problematic alcohol use. To date, we have ruled out drug-related vehicles of infection and identified few common risk factors.

Original language	English
Article number	30446
Journal	Eurosurveillance
Volume	22
Issue number	3
DOIs	https://doi.org/10.2807/1560-7917.ES.2017.22.3.30446
Publication status	Published - 19 Jan 2017

Bibliographical note

Funding Information:
We would like to thank all the cases for their cooperation with this investigation and the following people, listed in alphabetical order, for their role in investigating the outbreak: Adam Spencer, Brendan Mason, Chitra Arumugam, Chris Williams, Claude Seng, Dan Lewer, David Wainfur, Helen Trudgeon, Ian Greenwood, Jennifer Duffy, Jill Bonney, Julie Mann, Kathryn Wolf, Phil McHale, Laura Pomeroy, Liz Loosemore, Meera Chand, Mike Burrell, Oluwakemi Olufon, Richard Packer, Roger Daniel, Sarah Kennedy, Simon Padfield, Si?n Lingard, Sue Morgan, Victoria Moir, Zoe Gibson. The Blast-emm database is hosted by Centres for Disease Control and Prevention (https://www2a.cdc.gov/ncidod/biotech/ strepblast.asp) NB is funded by UK Field Epidemiology Training Programme (FETP), Public Health England, LB is funded by European Programme for Public Health Microbiology Training (EUPHEM), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden and DJ is funded by European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden. We would like to thank Sooria Balasegaram (FETP), Ioannis Karagiannis (FETP), Androulla Efstratiou (EUPHEM), Aftab Jasir (EUPHEM), Isabel Oliver (EPIET) and Lisa Hansen (EPIET) for the support provided to the fellows that they supervise.

Publisher Copyright:
© 2017, European Centre for Disease Prevention and Control (ECDC). All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.2807/1560-7917.ES.2017.22.3.30446

Cite this

Bundle, N., Bubba, L., Coelho, J., Kwiatkowska, R., Cloke, R., King, S., Rajan-Iyer, J., Courtney-Pillinger, M., Beck, C., Hope, V., Lamagni, T., Brown, C., Jermacane, D., Glass, R., Desai, M., Gobin, M., Balasegaram, S., & Anderson, C. (2017). Ongoing outbreak of invasive and non-invasive disease due to group a Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016. Eurosurveillance, 22(3), Article 30446. https://doi.org/10.2807/1560-7917.ES.2017.22.3.30446

@article{b49563f851404dcb94f4d7a749343958,

title = "Ongoing outbreak of invasive and non-invasive disease due to group a Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016",

abstract = "We report an outbreak of invasive and non-invasive disease due to an unusual type of Streptococcus pyogenes(group A Streptococcus, emm66) among a vulnerable, largely homeless population in southern England and Wales, detected in September 2016. Twenty-seven confirmed cases were subsequently identified between 5 January and 29 December 2016; 20 injected drugs and six reported problematic alcohol use. To date, we have ruled out drug-related vehicles of infection and identified few common risk factors.",

author = "Nicholas Bundle and L. Bubba and J. Coelho and R. Kwiatkowska and R. Cloke and S. King and J. Rajan-Iyer and M. Courtney-Pillinger and Charles Beck and V. Hope and Theresa Lamagni and Colin Brown and D. Jermacane and R. Glass and Monica Desai and Maya Gobin and S. Balasegaram and Charlotte Anderson",

note = "Funding Information: We would like to thank all the cases for their cooperation with this investigation and the following people, listed in alphabetical order, for their role in investigating the outbreak: Adam Spencer, Brendan Mason, Chitra Arumugam, Chris Williams, Claude Seng, Dan Lewer, David Wainfur, Helen Trudgeon, Ian Greenwood, Jennifer Duffy, Jill Bonney, Julie Mann, Kathryn Wolf, Phil McHale, Laura Pomeroy, Liz Loosemore, Meera Chand, Mike Burrell, Oluwakemi Olufon, Richard Packer, Roger Daniel, Sarah Kennedy, Simon Padfield, Si?n Lingard, Sue Morgan, Victoria Moir, Zoe Gibson. The Blast-emm database is hosted by Centres for Disease Control and Prevention (https://www2a.cdc.gov/ncidod/biotech/ strepblast.asp) NB is funded by UK Field Epidemiology Training Programme (FETP), Public Health England, LB is funded by European Programme for Public Health Microbiology Training (EUPHEM), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden and DJ is funded by European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden. We would like to thank Sooria Balasegaram (FETP), Ioannis Karagiannis (FETP), Androulla Efstratiou (EUPHEM), Aftab Jasir (EUPHEM), Isabel Oliver (EPIET) and Lisa Hansen (EPIET) for the support provided to the fellows that they supervise. Publisher Copyright: {\textcopyright} 2017, European Centre for Disease Prevention and Control (ECDC). All rights reserved.",

year = "2017",

month = jan,

day = "19",

doi = "10.2807/1560-7917.ES.2017.22.3.30446",

language = "English",

volume = "22",

journal = "Eurosurveillance",

issn = "1025-496X",

publisher = "European Centre for Disease Prevention and Control",

number = "3",

}

Bundle, N, Bubba, L, Coelho, J, Kwiatkowska, R, Cloke, R, King, S, Rajan-Iyer, J, Courtney-Pillinger, M, Beck, C, Hope, V, Lamagni, T , Brown, C, Jermacane, D, Glass, R, Desai, M, Gobin, M, Balasegaram, S & Anderson, C 2017, 'Ongoing outbreak of invasive and non-invasive disease due to group a Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016', Eurosurveillance, vol. 22, no. 3, 30446. https://doi.org/10.2807/1560-7917.ES.2017.22.3.30446

TY - JOUR

T1 - Ongoing outbreak of invasive and non-invasive disease due to group a Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016

AU - Bundle, Nicholas

AU - Bubba, L.

AU - Coelho, J.

AU - Kwiatkowska, R.

AU - Cloke, R.

AU - King, S.

AU - Rajan-Iyer, J.

AU - Courtney-Pillinger, M.

AU - Beck, Charles

AU - Hope, V.

AU - Lamagni, Theresa

AU - Brown, Colin

AU - Jermacane, D.

AU - Glass, R.

AU - Desai, Monica

AU - Gobin, Maya

AU - Balasegaram, S.

AU - Anderson, Charlotte

N1 - Funding Information: We would like to thank all the cases for their cooperation with this investigation and the following people, listed in alphabetical order, for their role in investigating the outbreak: Adam Spencer, Brendan Mason, Chitra Arumugam, Chris Williams, Claude Seng, Dan Lewer, David Wainfur, Helen Trudgeon, Ian Greenwood, Jennifer Duffy, Jill Bonney, Julie Mann, Kathryn Wolf, Phil McHale, Laura Pomeroy, Liz Loosemore, Meera Chand, Mike Burrell, Oluwakemi Olufon, Richard Packer, Roger Daniel, Sarah Kennedy, Simon Padfield, Si?n Lingard, Sue Morgan, Victoria Moir, Zoe Gibson. The Blast-emm database is hosted by Centres for Disease Control and Prevention (https://www2a.cdc.gov/ncidod/biotech/ strepblast.asp) NB is funded by UK Field Epidemiology Training Programme (FETP), Public Health England, LB is funded by European Programme for Public Health Microbiology Training (EUPHEM), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden and DJ is funded by European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden. We would like to thank Sooria Balasegaram (FETP), Ioannis Karagiannis (FETP), Androulla Efstratiou (EUPHEM), Aftab Jasir (EUPHEM), Isabel Oliver (EPIET) and Lisa Hansen (EPIET) for the support provided to the fellows that they supervise. Publisher Copyright: © 2017, European Centre for Disease Prevention and Control (ECDC). All rights reserved.

PY - 2017/1/19

Y1 - 2017/1/19

N2 - We report an outbreak of invasive and non-invasive disease due to an unusual type of Streptococcus pyogenes(group A Streptococcus, emm66) among a vulnerable, largely homeless population in southern England and Wales, detected in September 2016. Twenty-seven confirmed cases were subsequently identified between 5 January and 29 December 2016; 20 injected drugs and six reported problematic alcohol use. To date, we have ruled out drug-related vehicles of infection and identified few common risk factors.

AB - We report an outbreak of invasive and non-invasive disease due to an unusual type of Streptococcus pyogenes(group A Streptococcus, emm66) among a vulnerable, largely homeless population in southern England and Wales, detected in September 2016. Twenty-seven confirmed cases were subsequently identified between 5 January and 29 December 2016; 20 injected drugs and six reported problematic alcohol use. To date, we have ruled out drug-related vehicles of infection and identified few common risk factors.

UR - http://www.scopus.com/inward/record.url?scp=85010665754&partnerID=8YFLogxK

U2 - 10.2807/1560-7917.ES.2017.22.3.30446

DO - 10.2807/1560-7917.ES.2017.22.3.30446

M3 - Article

C2 - 28128090

AN - SCOPUS:85010665754

SN - 1025-496X

VL - 22

JO - Eurosurveillance

JF - Eurosurveillance

IS - 3

M1 - 30446

ER -

Ongoing outbreak of invasive and non-invasive disease due to group a Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016

Abstract

Bibliographical note

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this