Objective comparison of high-contrast spatial resolution and low-contrast detectability for various clinical protocols on multiple CT scanners

Damien Racine*, Anaïs Viry, Fabio Becce, Sabine Schmidt, Alexandre Ba, François O. Bochud, Sue Edyvean, Alexander Schegerer, Francis R. Verdun

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Purpose: We sought to compare objectively computed tomography (CT) scanner performance for three clinically relevant protocols using a task-based image quality assessment method in order to assess the potential for radiation dose reduction. Methods: Four CT scanners released between 2003 and 2007 by different manufacturers were compared with four CT scanners released between 2012 and 2014 by the same manufacturers using ideal linear model observers (MO): prewhitening (PW) MO and channelized Hotelling (CHO) MO with Laguerre-Gauss channels for high-contrast spatial resolution and low-contrast detectability (LCD) performance, respectively. High-contrast spatial resolution was assessed using a custom-made phantom that enabled the computation of the target transfer function (TTF) and noise power spectrum (NPS). Low-contrast detectability was assessed using a commercially available anthropomorphic abdominal phantom providing equivalent diameters of 24, 29.6, and 34.6 cm. Three protocols were reviewed: a head (trauma) and an abdominal (urinary stones) protocol were applied to assess high-contrast spatial resolution performance; and another abdominal (focal liver lesions) protocol was applied for LCD. The liver protocol was tested using fixed and modulated tube currents. The PW MO was proposed for assessing high-contrast detectability performance of the various CT scanners. Results: Compared with older generation CT scanners, three newer systems displayed significant improvements in high-contrast detectability over that of their predecessors. A fourth, newer system had lower performance. The CHO MO was appropriate for assessing LCD performance and revealed that an excellent level of image quality could be obtained with newer scanners at significantly lower dose levels. Conclusions: This study shows that MO can objectively benchmark CT scanners using a task-based image quality method, thus helping to estimate the potential for further dose reductions offered by the latest systems. Such an approach may be useful for adequately and quantitatively comparing clinically relevant image quality among various scanners.

Original languageEnglish
Pages (from-to)e153-e163
JournalMedical Physics
Issue number9
Publication statusPublished - Sep 2017

Bibliographical note

Funding Information:
This work was supported by the German Radiation Protection Agency (BfS – “UFO-Plan Vorhabens 3613S20007”). The authors thank Prof. Peter Vock and PD Dr Sebastian Schindera, the two other senior radiologists involved in this project for their help when dealing with the choice of the protocols and diagnostic tasks. The authors also thank MSc Pascal Monnin for his advices concerning the estimation of the TTF functions.

Publisher Copyright:
© 2017 The Authors. Medical Physics published by Wiley periodicals, Inc. on behalf of American Association of Physicists in Medicine.


  • computed tomography
  • high-contrast spatial resolution
  • image quality
  • low-contrast detectability
  • model observers


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