Novel use of capture-recapture methods to estimate completeness of contact tracing during an Ebola outbreak, Democratic Republic of the Congo, 2018-2020

Jonathan A. Polonsky, Dankmar Böhning, Mory Keita, Steve Ahuka-Mundeke, Justus Nsio-Mbeta, Aaron Aruna Abedi, Mathias Mossoko, Janne Estill, Olivia Keiser, Laurent Kaiser, Zabulon Yoti, Patarawan Sangnawakij, Rattana Lerdsuwansri, Victor J. Del Rio Vilas*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Despite its critical role in containing outbreaks, the efficacy of contact tracing, measured as the sensitivity of case detection, remains an elusive metric. We estimated the sensitivity of contact tracing by applying unilist capture-recapture methods on data from the 2018-2020 outbreak of Ebola virus disease in the Democratic Republic of the Congo. To compute sensitivity, we applied different distributional assumptions to the zero-truncated count data to estimate the number of unobserved case-patients with any contacts and infected contacts. Geometric distributions were the best-fitting models. Our results indicate that contact tracing efforts identified almost all (n = 792, 99%) of case-patients with any contacts but only half (n = 207, 48%) of case-patients with infected contacts, suggesting that contact tracing efforts performed well at identifying contacts during the listing stage but performed poorly during the contact follow-up stage. We discuss extensions to our work and potential applications for the ongoing coronavirus pandemic.

Original languageEnglish
Pages (from-to)3063-3072
Number of pages10
JournalEmerging Infectious Diseases
Volume27
Issue number12
DOIs
Publication statusPublished - Dec 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.

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