Novel staphylococcal species that form part of a Staphylococcus aureus-related complex: the non-pigmented Staphylococcus argenteus sp. nov. and the non-human primate-associated Staphylococcus schweitzeri sp. nov

Steven Y.C. Tong, Frieder Schaumburg, Matthew J. Ellington, Jukka Corander, Bruno Pichon, Fabian Leendertz, Stephen D. Bentley, Julian Parkhill, Deborah C. Holt, Georg Peters, Philip M. Giffard

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170 Citations (Scopus)

Abstract

We define two novel species of the genus Staphylococcus that are phenotypically similar to and have near identical 16S rRNA gene sequences toStaphylococcus aureus. However, compared to S. aureus and each other, the two species, Staphylococcus argenteus sp. nov. (type strain MSHR1132T = DSM 28299T = SSI 89.005T) and Staphylococcus schweitzeri sp. nov. (type strain FSA084T = DSM 28300T = SSI 89.004T), demonstrate: 1) at a whole-genome level considerable phylogenetic distance, lack of admixture, average nucleotide identity <95 %, and inferred DNA–DNA hybridization <70 %; 2) different profiles as determined by MALDI-TOF MS; 3) a non-pigmented phenotype for S. argenteus sp. nov.; 4) S. schweitzeri sp. nov. is not detected by standard nucA PCR; 5) distinct peptidoglycan types compared to S. aureus; 6) a separate ecological niche for S. schweitzeri sp. nov.; and 7) a distinct clinical disease profile for S. argenteus sp. nov. compared to S. aureus.

Original languageEnglish
Pages (from-to)15-22
Number of pages8
JournalInternational Journal of Systematic and Evolutionary Microbiology
Volume65
Issue number1
DOIs
Publication statusPublished - 1 Jan 2015

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