TY - JOUR
T1 - Nontoxigenic Corynebacterium diphtheriae
T2 - An emerging pathogen in England and Wales?
AU - Reacher, Mark
AU - Ramsay, Mary
AU - White, Joanne
AU - De Zoysa, Aruni
AU - Efstratiou, Androulla
AU - Mann, Gina
AU - Mackay, Andrew
AU - George, Robert
PY - 2000
Y1 - 2000
N2 - Confirmed isolates of nontoxigenic Corynebacterium diphtheriae in England and Wales increased substantially from 1986 to 1994. Ribotyping of 121 isolates confirmed in 1995 showed that 90 were of a single strain isolated exclusively from the throat; none had previously been identified in toxigenic strains from U.K. or non-U.K. residents. The upward trend in nontoxigenic C. diphtheriae probably represented increased ascertainment, although dissemination of a particular strain or clone may have been a factor.
AB - Confirmed isolates of nontoxigenic Corynebacterium diphtheriae in England and Wales increased substantially from 1986 to 1994. Ribotyping of 121 isolates confirmed in 1995 showed that 90 were of a single strain isolated exclusively from the throat; none had previously been identified in toxigenic strains from U.K. or non-U.K. residents. The upward trend in nontoxigenic C. diphtheriae probably represented increased ascertainment, although dissemination of a particular strain or clone may have been a factor.
UR - http://www.scopus.com/inward/record.url?scp=0034488905&partnerID=8YFLogxK
U2 - 10.3201/eid0606.00614
DO - 10.3201/eid0606.00614
M3 - Article
C2 - 11076724
AN - SCOPUS:0034488905
SN - 1080-6040
VL - 6
SP - 640
EP - 645
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 6
ER -