Nontoxigenic Corynebacterium diphtheriae: An emerging pathogen in England and Wales?

Mark Reacher*, Mary Ramsay, Joanne White, Aruni De Zoysa, Androulla Efstratiou, Gina Mann, Andrew Mackay, Robert George

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)

Abstract

Confirmed isolates of nontoxigenic Corynebacterium diphtheriae in England and Wales increased substantially from 1986 to 1994. Ribotyping of 121 isolates confirmed in 1995 showed that 90 were of a single strain isolated exclusively from the throat; none had previously been identified in toxigenic strains from U.K. or non-U.K. residents. The upward trend in nontoxigenic C. diphtheriae probably represented increased ascertainment, although dissemination of a particular strain or clone may have been a factor.

Original languageEnglish
Pages (from-to)640-645
Number of pages6
JournalEmerging Infectious Diseases
Volume6
Issue number6
DOIs
Publication statusPublished - 2000

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