NCTC3000: a century of bacterial strain collecting leads to a rich genomic data resource

Jo Dicks, Mohammed Abbas Fazal, Karen Oliver, Nicholas E. Grayson, Jake D. Turnbull, Evangeline Bane, Edward Burnett, Ana Deheer-Graham, Nancy Holroyd, Dorota Kaushal, Jacqueline Keane, Gemma Langridge, Jane Lomax, Hannah McGregor, Steve Picton, Michael Quail, Deepak Singh, Alan Tracey, Jonas Korlach, Julie E. RussellSarah Alexander*, Julian Parkhill*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


The National Collection of Type Cultures (NCTC) was founded on 1 January 1920 in order to fulfil a recognized need for a centralized repository for bacterial and fungal strains within the UK. It is among the longest-established collections of its kind anywhere in the world and today holds approximately 6000 type and reference bacterial strains – many of medical, scientific and veterinary importance – available to academic, health, food and veterinary institutions worldwide. Recently, a collaboration between NCTC, Pacific Biosciences and the Wellcome Sanger Institute established the NCTC3000 project to long-read sequence and assemble the genomes of up to 3000 NCTC strains. Here, at the beginning of the collection’s second century, we introduce the resulting NCTC3000 sequence read datasets, genome assemblies and annotations as a unique, historically and scientifically relevant resource for the benefit of the international bacterial research community.

Original languageEnglish
Article number000976
JournalMicrobial Genomics
Issue number5
Publication statusPublished - 1 May 2023

Bibliographical note

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  • National collection of type cultures
  • bacterial genomes
  • genome assemblies
  • pacific bioscience long reads


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