Multidisciplinary European Low Dose Initiative (MELODI): strategic research agenda for low dose radiation risk research

M. Kreuzer*, A. Auvinen, E. Cardis, M. Durante, M. Harms-Ringdahl, J. R. Jourdain, B. G. Madas, A. Ottolenghi, S. Pazzaglia, K. M. Prise, R. Quintens, L. Sabatier, S. Bouffler

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

31 Citations (Scopus)


MELODI (Multidisciplinary European Low Dose Initiative) is a European radiation protection research platform with focus on research on health risks after exposure to low-dose ionising radiation. It was founded in 2010 and currently includes 44 members from 18 countries. A major activity of MELODI is the continuous development of a long-term European Strategic Research Agenda (SRA) on low-dose risk for radiation protection. The SRA is intended to identify priorities for national and European radiation protection research programs as a basis for the preparation of competitive calls at the European level. Among those key priorities is the improvement of health risk estimates for exposures close to the dose limits for workers and to reference levels for the population in emergency situations. Another activity of MELODI is to ensure the availability of European key infrastructures for research activities, and the long-term maintenance of competences in radiation research via an integrated European approach for training and education. The MELODI SRA identifies three key research topics in low dose or low dose-rate radiation risk research: (1) dose and dose rate dependence of cancer risk, (2) radiation-induced non-cancer effects and (3) individual radiation sensitivity. The research required to improve the evidence base for each of the three key topics relates to three research lines: (1) research to improve understanding of the mechanisms contributing to radiogenic diseases, (2) epidemiological research to improve health risk evaluation of radiation exposure and (3) research to address the effects and risks associated with internal exposures, differing radiation qualities and inhomogeneous exposures. The full SRA and associated documents can be downloaded from the MELODI website (

Original languageEnglish
Pages (from-to)5-15
Number of pages11
JournalRadiation and Environmental Biophysics
Issue number1
Publication statusPublished - 1 Mar 2018

Bibliographical note

Funding Information:
Funding The research leading to these results has received funding from the European Atomic Energy Community Seventh Framework Programme FP7/2007–2011 under Grant agreement no. 249689 (DoReMi), the European Union’s Seventh Framework Programme (FP7/2007–2013) under Grant agreement no. 604984 (OPERRA) and from the Euratom research and training programme 2014–2018 under Grant agreement no. 662287 (CONCERT).

Publisher Copyright:
© 2017, The Author(s).


  • Cancer
  • Health effects
  • Individual sensitivity
  • Ionizing radiation
  • Low-dose
  • Non-cancer


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