Morbidity and mortality associated with Clostridium difficile ribotype 078: A case-case study

L. Patterson; M. H. Wilcox; W. N. Fawley; Neville Verlander; L. Geoghegan; B. C. Patel; T. Wyatt; B. Smyth

doi:10.1016/j.jhin.2012.07.011

Morbidity and mortality associated with Clostridium difficile ribotype 078: A case-case study

L. Patterson^*, M. H. Wilcox, W. N. Fawley, Neville Verlander, L. Geoghegan, B. C. Patel, T. Wyatt, B. Smyth

^*Corresponding author for this work

Statistics Unit

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The morbidity and mortality associated with Clostridium difficile ribotype 078 were examined by comparison with other known outbreak strains. A healthcare interaction within eight weeks of a positive specimen significantly increased the likelihood of ribotype 078 compared with ribotype 027. Individuals with ribotype 078 also tended to come from community sources, have a hospital stay post specimen similar to ribotype 027 and a lower 30-day mortality, but these differences were not statistically significant. This study generates several hypotheses and a methodological platform to explore this unique profile.

Original language	English
Pages (from-to)	125-128
Number of pages	4
Journal	Journal of Hospital Infection
Volume	82
Issue number	2
DOIs	https://doi.org/10.1016/j.jhin.2012.07.011
Publication status	Published - Oct 2012

Keywords

Clostridium difficile
Community
Mortality
Ribotype 078

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jhin.2012.07.011

Cite this

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title = "Morbidity and mortality associated with Clostridium difficile ribotype 078: A case-case study",

abstract = "The morbidity and mortality associated with Clostridium difficile ribotype 078 were examined by comparison with other known outbreak strains. A healthcare interaction within eight weeks of a positive specimen significantly increased the likelihood of ribotype 078 compared with ribotype 027. Individuals with ribotype 078 also tended to come from community sources, have a hospital stay post specimen similar to ribotype 027 and a lower 30-day mortality, but these differences were not statistically significant. This study generates several hypotheses and a methodological platform to explore this unique profile.",

keywords = "Clostridium difficile, Community, Mortality, Ribotype 078",

author = "L. Patterson and Wilcox, {M. H.} and Fawley, {W. N.} and Neville Verlander and L. Geoghegan and Patel, {B. C.} and T. Wyatt and B. Smyth",

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AU - Patterson, L.

AU - Wilcox, M. H.

AU - Fawley, W. N.

AU - Verlander, Neville

AU - Geoghegan, L.

AU - Patel, B. C.

AU - Wyatt, T.

AU - Smyth, B.

PY - 2012/10

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N2 - The morbidity and mortality associated with Clostridium difficile ribotype 078 were examined by comparison with other known outbreak strains. A healthcare interaction within eight weeks of a positive specimen significantly increased the likelihood of ribotype 078 compared with ribotype 027. Individuals with ribotype 078 also tended to come from community sources, have a hospital stay post specimen similar to ribotype 027 and a lower 30-day mortality, but these differences were not statistically significant. This study generates several hypotheses and a methodological platform to explore this unique profile.

AB - The morbidity and mortality associated with Clostridium difficile ribotype 078 were examined by comparison with other known outbreak strains. A healthcare interaction within eight weeks of a positive specimen significantly increased the likelihood of ribotype 078 compared with ribotype 027. Individuals with ribotype 078 also tended to come from community sources, have a hospital stay post specimen similar to ribotype 027 and a lower 30-day mortality, but these differences were not statistically significant. This study generates several hypotheses and a methodological platform to explore this unique profile.

KW - Clostridium difficile

KW - Community

KW - Mortality

KW - Ribotype 078

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AN - SCOPUS:84866350353

SN - 0195-6701

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JF - Journal of Hospital Infection

IS - 2

ER -

Morbidity and mortality associated with Clostridium difficile ribotype 078: A case-case study

Abstract

Keywords

UN SDGs

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