TY - JOUR
T1 - Monkeypox — Enhancing public health preparedness for an emerging lethal human zoonotic epidemic threat in the wake of the smallpox post-eradication era
AU - Petersen, Eskild
AU - Abubakar, Ibrahim
AU - Ihekweazu, Chikwe
AU - Heymann, David
AU - Ntoumi, Francine
AU - Blumberg, Lucille
AU - Asogun, Danny
AU - Mukonka, Victor
AU - Lule, Swaib Abubaker
AU - Bates, Matthew
AU - Honeyborne, Isobella
AU - Mfinanga, Sayoki
AU - Mwaba, Peter
AU - Dar, Osman
AU - Vairo, Francesco
AU - Mukhtar, Maowia
AU - Kock, Richard
AU - McHugh, Tim
AU - Ippolito, Giuseppe
AU - Zumla, Alimuddin
N1 - Publisher Copyright:
© 2018 The Author(s)
PY - 2019/1
Y1 - 2019/1
N2 - The identification of monkeypox in 3 separate patients in the United Kingdom in September raised media and political attention on an emerging public health threat. Nigeria, whose last confirmed case of monkeypox was in 1978, is currently experiencing an unusually large and outbreak of human monkeypox cases, a ‘One Human-Environmental-Animal Health’ approach is being effectively used to define and tackle the outbreak. As of 13th October 2018, there have been one hundred and sixteen confirmed cases the majority of whom are under 40 years. Over the past 20 years ten Central and West African countries have reported monkeypox cases which have risen exponentially. We review the history and evolution of monkeypox outbreaks in Africa and USA, the changing clinical presentations, and discuss possible factors underlying the increasing numbers being detected including the cessation of smallpox vaccination programs. Major knowledge gaps remain on the epidemiology, host reservoir, and emergence, transmission, pathogenesis and prevention of monkeypoz.
AB - The identification of monkeypox in 3 separate patients in the United Kingdom in September raised media and political attention on an emerging public health threat. Nigeria, whose last confirmed case of monkeypox was in 1978, is currently experiencing an unusually large and outbreak of human monkeypox cases, a ‘One Human-Environmental-Animal Health’ approach is being effectively used to define and tackle the outbreak. As of 13th October 2018, there have been one hundred and sixteen confirmed cases the majority of whom are under 40 years. Over the past 20 years ten Central and West African countries have reported monkeypox cases which have risen exponentially. We review the history and evolution of monkeypox outbreaks in Africa and USA, the changing clinical presentations, and discuss possible factors underlying the increasing numbers being detected including the cessation of smallpox vaccination programs. Major knowledge gaps remain on the epidemiology, host reservoir, and emergence, transmission, pathogenesis and prevention of monkeypoz.
UR - http://www.scopus.com/inward/record.url?scp=85056979811&partnerID=8YFLogxK
U2 - 10.1016/j.ijid.2018.11.008
DO - 10.1016/j.ijid.2018.11.008
M3 - Editorial
C2 - 30453097
AN - SCOPUS:85056979811
SN - 1201-9712
VL - 78
SP - 78
EP - 84
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
ER -