Molecular epidemiology of Mycobacterium avium complex isolated from patients with and without AIDS in Brazil and England

M. A.S. Telles; M. D. Yates; M. Curcio; S. Y.M. Ueki; M. Palaci; D. J. Hadad; Francis Drobniewski; A. L. Pozniak

doi:10.1017/S0950268899002459

Molecular epidemiology of Mycobacterium avium complex isolated from patients with and without AIDS in Brazil and England

M. A.S. Telles, M. D. Yates^*, M. Curcio, S. Y.M. Ueki, M. Palaci, D. J. Hadad, Francis Drobniewski, A. L. Pozniak

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Mycobacterium avium complex (MAC) is ubiquitous throughout the world. It is an opportunistic pathogen in AIDS patients but the number of cases in HIV negative patients is also increasing. The aim of this study was to determine whether patients were being infected with different MAC strains or whether one strain was dominant. DNA obtained from isolates in Brazil and England were compared using pulsed field gel electrophoresis (PFGE). Strains from 22 Brazilian patients clustered into 7 groups but 68/90 patients had a unique strain. In all patients, Brazilian and English, the same strain was isolated repeatedly over time, some over several years. This study shows that it is most likely that Man is infected from the environment and that one strain can survive without change for many years both in the environment and in Man.

Original language	English
Pages (from-to)	435-440
Number of pages	6
Journal	Epidemiology and Infection
Volume	122
Issue number	3
DOIs	https://doi.org/10.1017/S0950268899002459
Publication status	Published - Jun 1999

Bibliographical note

Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1017/S0950268899002459

Cite this

@article{b1b6149f22d84d0896b0b3a8ec9390d4,

title = "Molecular epidemiology of Mycobacterium avium complex isolated from patients with and without AIDS in Brazil and England",

abstract = "Mycobacterium avium complex (MAC) is ubiquitous throughout the world. It is an opportunistic pathogen in AIDS patients but the number of cases in HIV negative patients is also increasing. The aim of this study was to determine whether patients were being infected with different MAC strains or whether one strain was dominant. DNA obtained from isolates in Brazil and England were compared using pulsed field gel electrophoresis (PFGE). Strains from 22 Brazilian patients clustered into 7 groups but 68/90 patients had a unique strain. In all patients, Brazilian and English, the same strain was isolated repeatedly over time, some over several years. This study shows that it is most likely that Man is infected from the environment and that one strain can survive without change for many years both in the environment and in Man.",

author = "Telles, {M. A.S.} and Yates, {M. D.} and M. Curcio and Ueki, {S. Y.M.} and M. Palaci and Hadad, {D. J.} and Francis Drobniewski and Pozniak, {A. L.}",

year = "1999",

month = jun,

doi = "10.1017/S0950268899002459",

language = "English",

volume = "122",

pages = "435--440",

journal = "Epidemiology and Infection",

issn = "0950-2688",

publisher = "Cambridge University Press",

number = "3",

}

TY - JOUR

T1 - Molecular epidemiology of Mycobacterium avium complex isolated from patients with and without AIDS in Brazil and England

AU - Telles, M. A.S.

AU - Yates, M. D.

AU - Curcio, M.

AU - Ueki, S. Y.M.

AU - Palaci, M.

AU - Hadad, D. J.

AU - Drobniewski, Francis

AU - Pozniak, A. L.

PY - 1999/6

Y1 - 1999/6

N2 - Mycobacterium avium complex (MAC) is ubiquitous throughout the world. It is an opportunistic pathogen in AIDS patients but the number of cases in HIV negative patients is also increasing. The aim of this study was to determine whether patients were being infected with different MAC strains or whether one strain was dominant. DNA obtained from isolates in Brazil and England were compared using pulsed field gel electrophoresis (PFGE). Strains from 22 Brazilian patients clustered into 7 groups but 68/90 patients had a unique strain. In all patients, Brazilian and English, the same strain was isolated repeatedly over time, some over several years. This study shows that it is most likely that Man is infected from the environment and that one strain can survive without change for many years both in the environment and in Man.

AB - Mycobacterium avium complex (MAC) is ubiquitous throughout the world. It is an opportunistic pathogen in AIDS patients but the number of cases in HIV negative patients is also increasing. The aim of this study was to determine whether patients were being infected with different MAC strains or whether one strain was dominant. DNA obtained from isolates in Brazil and England were compared using pulsed field gel electrophoresis (PFGE). Strains from 22 Brazilian patients clustered into 7 groups but 68/90 patients had a unique strain. In all patients, Brazilian and English, the same strain was isolated repeatedly over time, some over several years. This study shows that it is most likely that Man is infected from the environment and that one strain can survive without change for many years both in the environment and in Man.

UR - http://www.scopus.com/inward/record.url?scp=0032780370&partnerID=8YFLogxK

U2 - 10.1017/S0950268899002459

DO - 10.1017/S0950268899002459

M3 - Article

C2 - 10459647

AN - SCOPUS:0032780370

SN - 0950-2688

VL - 122

SP - 435

EP - 440

JO - Epidemiology and Infection

JF - Epidemiology and Infection

IS - 3

ER -

Molecular epidemiology of Mycobacterium avium complex isolated from patients with and without AIDS in Brazil and England

Abstract

Bibliographical note

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this