TY - JOUR
T1 - Migration and tuberculosis in the UK
T2 - Targeting screening for latent infection to those at greatest risk of disease
AU - Kruijshaar, Michelle E.
AU - Abubakar, Ibrahim
AU - Stagg, Helen R.
AU - Pedrazzoli, Debora
AU - Lipman, Marc
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013/12
Y1 - 2013/12
N2 - Active tuberculosis (TB) in the UK predominantly affects the non-UK born, but is generally not manifest at the time of UK entry. Strategies to detect latent TB infection (LTBI) in this population are, therefore, important. To date, targeted screening has focused on TB risk estimates based on the incidence in the country of origin. Using TB incidence in the UK and migration data, we estimated the numbers needed to be tested and treated for LTBI to prevent one case of TB disease. Numbers were the lowest in Somalian and the highest in South African and Filipino migrants, which contrasts with TB rates in these countries. Targeting screening on the basis of incidence in the UK may thus improve effectiveness.
AB - Active tuberculosis (TB) in the UK predominantly affects the non-UK born, but is generally not manifest at the time of UK entry. Strategies to detect latent TB infection (LTBI) in this population are, therefore, important. To date, targeted screening has focused on TB risk estimates based on the incidence in the country of origin. Using TB incidence in the UK and migration data, we estimated the numbers needed to be tested and treated for LTBI to prevent one case of TB disease. Numbers were the lowest in Somalian and the highest in South African and Filipino migrants, which contrasts with TB rates in these countries. Targeting screening on the basis of incidence in the UK may thus improve effectiveness.
UR - http://www.scopus.com/inward/record.url?scp=84887485552&partnerID=8YFLogxK
U2 - 10.1136/thoraxjnl-2013-203254
DO - 10.1136/thoraxjnl-2013-203254
M3 - Article
C2 - 23828120
AN - SCOPUS:84887485552
SN - 0040-6376
VL - 68
SP - 1172
EP - 1174
JO - Thorax
JF - Thorax
IS - 12
ER -