Methicillin-resistant Staphylococcus aureus: The European landscape

Alan Johnson*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

166 Citations (Scopus)


Pan-European surveillance of bacteraemia caused by methicillin-resistant Staphylococcus aureus (MRSA) shows it to be a problem affecting all European countries, although there is marked geographical variation in prevalence. Although the proportion of S. aureus bacteraemia due to MRSA is declining in many countries, data from the European Antimicrobial Resistance Surveillance System (EARSS) for 2008 showed that in more than onethird of countries the proportion remained .25%. In contrast to bacteraemia, community-associated MRSA infection in Europe remains relatively uncommon. However, there appears to be an increasing problem involving transmission of MRSA (particularly sequence type 398) from colonized livestock, particularly pigs, to farm workers, abattoir workers and veterinarians who are in contact with such animals. Molecular analysis of isolates of MRSA has shown that there has been spread of only a limited number of MRSA clones in Europe and that many of these clones show geographical clustering due to dissemination through regional healthcare networks. Despite our increasing understanding of the epidemiology of MRSA in Europe, MRSA infections continue to pose a significant public health challenge.

Original languageEnglish
Article numberdkr076
Pages (from-to)iv43-iv48
JournalJournal of Antimicrobial Chemotherapy
Issue numberSUPPL. 4
Publication statusPublished - May 2011

Bibliographical note

Funding Information:
This article is part of a Supplement sponsored by the BSAC and supported by an unrestricted educational grant from Pfizer. The author received an honorarium from the BSAC for writing this article. The author is Editor-in-Chief of the Journal of Antimicrobial Chemotherapy but took no part in and did not influence the editing of this manuscript. The author has no other conflicts of interest to declare.


  • Bacteraemia
  • MRSA
  • Staphylococcal infections
  • Surveillance


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