Measles vaccine efficacy during an epidemic in 1998 in the highly vaccinated population of Poland

Wieslawa Janaszek; Nigel J. Gay; Wlodzimierz Gut

doi:10.1016/S0264-410X(02)00482-6

Measles vaccine efficacy during an epidemic in 1998 in the highly vaccinated population of Poland

Wieslawa Janaszek^*, Nigel J. Gay, Wlodzimierz Gut

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

A measles epidemic with 2255 reported cases occurred in Poland between November 1997 and July 1998, despite high vaccination coverage since the 1980s. Cases occurred at all ages less than 30 years but showed two distinct peaks: young, unvaccinated children born in 1996-1997 and once vaccinated young adults born 1976-1982. The 60% of cases were among persons aged 15 years or more. A cohort study was used to investigate measles vaccine efficacy. The efficacy of a single dose of vaccine exceeded 90% and the efficacy of two doses exceeded 99% in all age-groups. These results demonstrate both the high efficacy of the monovalent measles vaccines used in Poland and the benefit of a second dose of vaccine.

Original language	English
Pages (from-to)	473-478
Number of pages	6
Journal	Vaccine
Volume	21
Issue number	5-6
DOIs	https://doi.org/10.1016/S0264-410X(02)00482-6
Publication status	Published - 17 Jan 2003

Bibliographical note

Funding Information:
Funding for this project was received from the WHO Department of Vaccines and Biologicals.

Keywords

Efficacy
Measles
Vaccine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0264-410X(02)00482-6

Cite this

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abstract = "A measles epidemic with 2255 reported cases occurred in Poland between November 1997 and July 1998, despite high vaccination coverage since the 1980s. Cases occurred at all ages less than 30 years but showed two distinct peaks: young, unvaccinated children born in 1996-1997 and once vaccinated young adults born 1976-1982. The 60% of cases were among persons aged 15 years or more. A cohort study was used to investigate measles vaccine efficacy. The efficacy of a single dose of vaccine exceeded 90% and the efficacy of two doses exceeded 99% in all age-groups. These results demonstrate both the high efficacy of the monovalent measles vaccines used in Poland and the benefit of a second dose of vaccine.",

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AB - A measles epidemic with 2255 reported cases occurred in Poland between November 1997 and July 1998, despite high vaccination coverage since the 1980s. Cases occurred at all ages less than 30 years but showed two distinct peaks: young, unvaccinated children born in 1996-1997 and once vaccinated young adults born 1976-1982. The 60% of cases were among persons aged 15 years or more. A cohort study was used to investigate measles vaccine efficacy. The efficacy of a single dose of vaccine exceeded 90% and the efficacy of two doses exceeded 99% in all age-groups. These results demonstrate both the high efficacy of the monovalent measles vaccines used in Poland and the benefit of a second dose of vaccine.

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Measles vaccine efficacy during an epidemic in 1998 in the highly vaccinated population of Poland

Abstract

Bibliographical note

Keywords

UN SDGs

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