Long-term follow-up of off-pump and on-pump coronary artery bypass grafting

Shahzad G. Raja*, Umberto Benedetto, Dimple Chudasama, Siobhan Daley, Mubassher Husain, Mohamed Amrani

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Objective: Despite increasing recognition of the benefits of off-pump coronary artery bypass grafting (CABG), concerns persist regarding its impact on long-term mortality and freedom from reintervention. In this study, we assessed the impact of off-pump CABG on long-term outcomes. Methods: From January 2002 to December 2002, a total of 307 consecutive patients who underwent isolated multivessel off-pump CABG at our institution were compared with a control group of 397 patients who underwent multivessel on-pump CABG during the same period. Perioperative data were prospectively collected and compared. In addition, univariate and risk-adjusted comparisons between the two groups were performed at 10 years. Results: After adjusting for clinical covariates, off-pump CABG did not emerge as a significant independent predictor of long-term mortality [hazard ratio (HR), 0.91; 95% confidence interval (CI), 0.70-1.12], readmission to hospital for cardiac cause (HR, 0.96; 95% CI, 0.78-1.10), or the need for reintervention (HR, 0.93; 95% CI, 0.87-1.05). Conclusions: At long-term follow-up, off-pump CABG remains a safe and effective myocardial revascularization strategy with no adverse impact on survival or freedom from reintervention.

Original languageEnglish
Pages (from-to)122-129
Number of pages8
JournalInnovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Issue number2
Publication statusPublished - 2014
Externally publishedYes


  • Cardiopulmonary bypass
  • Coronary artery bypass grafting
  • Myocardial revascularization
  • Off-pump coronary artery bypass grafting
  • On-pump coronary artery bypass grafting


Dive into the research topics of 'Long-term follow-up of off-pump and on-pump coronary artery bypass grafting'. Together they form a unique fingerprint.

Cite this