Locations of mouse DNA damage response and repair loci, and cancer risk modifiers

Robert A. Bulman; Tommaso A. Dragani; Simon D. Bouffler; Roger Cox

doi:10.1016/j.dnarep.2005.10.001

Locations of mouse DNA damage response and repair loci, and cancer risk modifiers

Robert A. Bulman^*
, Tommaso A. Dragani
, Simon D. Bouffler
, Roger Cox

^*Corresponding author for this work

Chief Scientific Officer Group Office

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

An outline is presented of an electronically accessible database that compares the locations of mouse genes involved in DNA repair, apoptosis, cell cycle and signal transduction with those of known cancer risk modifier genes. The database has a primary but not exclusive focus on modifiers of ionizing radiation (IR) cancer risk and genes involved in IR-induced DNA damage responses. The database (http://www.hpa.org.uk/radiation/publications/ misc_publications/dna_database/dna_database.htm) provides a useful tool for assessing the role of DNA damage response genes in cancer predisposition. Crown

Original language	English
Pages (from-to)	274-277
Number of pages	4
Journal	DNA Repair
Volume	5
Issue number	2
DOIs	https://doi.org/10.1016/j.dnarep.2005.10.001
Publication status	Published - 3 Feb 2006

Bibliographical note

Funding Information:
The compilation of the database was funded by the European Commission through the Fifth Framework MAGELLANS contract (FIGH-CT-1999-00006) as a joint collaborative research project involving the former National Radiological Protection Board, now the Radiation Protection Division of the Health Protection Agency (United Kingdom), and Istituto Nazionale Tumori (INT, Italy).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer
DNA repair
Ionizing radiation

Access to Document

10.1016/j.dnarep.2005.10.001

Cite this

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title = "Locations of mouse DNA damage response and repair loci, and cancer risk modifiers",

abstract = "An outline is presented of an electronically accessible database that compares the locations of mouse genes involved in DNA repair, apoptosis, cell cycle and signal transduction with those of known cancer risk modifier genes. The database has a primary but not exclusive focus on modifiers of ionizing radiation (IR) cancer risk and genes involved in IR-induced DNA damage responses. The database (http://www.hpa.org.uk/radiation/publications/ misc\_publications/dna\_database/dna\_database.htm) provides a useful tool for assessing the role of DNA damage response genes in cancer predisposition. Crown",

keywords = "Cancer, DNA repair, Ionizing radiation",

author = "Bulman, \{Robert A.\} and Dragani, \{Tommaso A.\} and Bouffler, \{Simon D.\} and Roger Cox",

note = "Funding Information: The compilation of the database was funded by the European Commission through the Fifth Framework MAGELLANS contract (FIGH-CT-1999-00006) as a joint collaborative research project involving the former National Radiological Protection Board, now the Radiation Protection Division of the Health Protection Agency (United Kingdom), and Istituto Nazionale Tumori (INT, Italy). ",

year = "2006",

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doi = "10.1016/j.dnarep.2005.10.001",

language = "English",

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pages = "274--277",

journal = "DNA Repair",

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TY - JOUR

T1 - Locations of mouse DNA damage response and repair loci, and cancer risk modifiers

AU - Bulman, Robert A.

AU - Dragani, Tommaso A.

AU - Bouffler, Simon D.

AU - Cox, Roger

N1 - Funding Information: The compilation of the database was funded by the European Commission through the Fifth Framework MAGELLANS contract (FIGH-CT-1999-00006) as a joint collaborative research project involving the former National Radiological Protection Board, now the Radiation Protection Division of the Health Protection Agency (United Kingdom), and Istituto Nazionale Tumori (INT, Italy).

PY - 2006/2/3

Y1 - 2006/2/3

N2 - An outline is presented of an electronically accessible database that compares the locations of mouse genes involved in DNA repair, apoptosis, cell cycle and signal transduction with those of known cancer risk modifier genes. The database has a primary but not exclusive focus on modifiers of ionizing radiation (IR) cancer risk and genes involved in IR-induced DNA damage responses. The database (http://www.hpa.org.uk/radiation/publications/ misc_publications/dna_database/dna_database.htm) provides a useful tool for assessing the role of DNA damage response genes in cancer predisposition. Crown

AB - An outline is presented of an electronically accessible database that compares the locations of mouse genes involved in DNA repair, apoptosis, cell cycle and signal transduction with those of known cancer risk modifier genes. The database has a primary but not exclusive focus on modifiers of ionizing radiation (IR) cancer risk and genes involved in IR-induced DNA damage responses. The database (http://www.hpa.org.uk/radiation/publications/ misc_publications/dna_database/dna_database.htm) provides a useful tool for assessing the role of DNA damage response genes in cancer predisposition. Crown

KW - Cancer

KW - DNA repair

KW - Ionizing radiation

UR - https://www.scopus.com/pages/publications/30344462085

U2 - 10.1016/j.dnarep.2005.10.001

DO - 10.1016/j.dnarep.2005.10.001

M3 - Article

C2 - 16290248

AN - SCOPUS:30344462085

SN - 1568-7864

VL - 5

SP - 274

EP - 277

JO - DNA Repair

JF - DNA Repair

IS - 2

ER -

Locations of mouse DNA damage response and repair loci, and cancer risk modifiers

Abstract

Bibliographical note

UN SDGs

Keywords

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