Live attenuated influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children two to six years of age in England in the 2015/16 season

Richard Pebody; B. Sile; F. Warburton; M. Sinnathamby; C. Tsang; Hongxin Zhao; Joanna Ellis; Nicholas Andrews

doi:10.2807/1560-7917.ES.2017.22.4.30450

Live attenuated influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children two to six years of age in England in the 2015/16 season

Richard Pebody^*, B. Sile, F. Warburton, M. Sinnathamby, C. Tsang, Hongxin Zhao, Joanna Ellis, Nicholas Andrews

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

The United Kingdom is introducing a universal annual influenza vaccination programme for children. Live attenuated influenza vaccine (LAIV) effectiveness (VE) against laboratory-confirmed influenza hospitalisation in 2 to 6 year-olds in England was measured in 2015/16 using the screening method. VE adjusted for age, geography and month was 54.5% (95% confidence interval (CI): 31.5% to 68.4%) for all influenza types combined; 48.3% (95% CI: 16.9% to 67.8%) for A(H₁N₁)pdm09 and 70.6% (95% CI: 33.2% to 87.1%) for B. The findings support on-going programme roll-out.

Original language	English
Journal	Eurosurveillance
Volume	22
Issue number	4
DOIs	https://doi.org/10.2807/1560-7917.ES.2017.22.4.30450
Publication status	Published - Jan 2017

Bibliographical note

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© European Centre for Disease Prevention and Control (ECDC). All rights reserved.

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10.2807/1560-7917.ES.2017.22.4.30450

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title = "Live attenuated influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children two to six years of age in England in the 2015/16 season",

abstract = "The United Kingdom is introducing a universal annual influenza vaccination programme for children. Live attenuated influenza vaccine (LAIV) effectiveness (VE) against laboratory-confirmed influenza hospitalisation in 2 to 6 year-olds in England was measured in 2015/16 using the screening method. VE adjusted for age, geography and month was 54.5% (95% confidence interval (CI): 31.5% to 68.4%) for all influenza types combined; 48.3% (95% CI: 16.9% to 67.8%) for A(H1N1)pdm09 and 70.6% (95% CI: 33.2% to 87.1%) for B. The findings support on-going programme roll-out.",

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AU - Sile, B.

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AU - Sinnathamby, M.

AU - Tsang, C.

AU - Zhao, Hongxin

AU - Ellis, Joanna

AU - Andrews, Nicholas

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Live attenuated influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children two to six years of age in England in the 2015/16 season

Abstract

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