Life-threatening parvovirus B19 - Associated myocarditis and cardiac transplantation as possible therapy: Two case reports

G. Enders*, J. Dötsch, J. Bauer, W. Nützenadel, H. Hengel, D. Haffner, G. Schalasta, K. Searle, K. E. Brown

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

62 Citations (Scopus)

Abstract

Parvovirus B19 infection can cause a wide spectrum of disease syndromes. Two cases of parvovirus B 19 infection were identified that resulted in life- threatening myocarditis shortly after acute infection in immunocompetent individuals. The diagnosis was made with serological and polymerase chain reaction techniques. One patient was successfully treated by heart transplantation. Sequence analysis showed that the parvovirus B19 cloned from the patients' sera had 99% homology with the prototype sequence. Clinicians should be alerted to the possible role of parvovirus B19 in myocarditis presenting in immunocompetent patients.

Original languageEnglish
Pages (from-to)355-358
Number of pages4
JournalClinical Infectious Diseases
Volume26
Issue number2
DOIs
Publication statusPublished - 1998

Fingerprint

Dive into the research topics of 'Life-threatening parvovirus B19 - Associated myocarditis and cardiac transplantation as possible therapy: Two case reports'. Together they form a unique fingerprint.

Cite this